Alkaline Stress Response in Enterococcus faecalis: Adaptation, Cross-Protection, and Changes in Protein Synthesis

Sigrid Flahaut (1) , Axel Hartke (1) , Jean-Christophe Giard (1) , Yanick Auffray (1)

1 LME - Laboratoire de Microbiologie de l’Environnement

The alkaline shock response in Enterococcus faecalis was studied in this work. Cells adapted to an optimum pH of 10.5 were tolerant to pH 11.9 conditions but acquired sensitivity to acid damage. An analysis of stress proteins revealed that 37 polypeptides were amplified. Two of these are DnaK and GroEL. The combined results show that bile salts and alkaline stress responses are closely related.

Domaines: Bactériologie

Sigrid Flahaut, Axel Hartke, Jean-Christophe Giard, Yanick Auffray. Alkaline Stress Response in Enterococcus faecalis: Adaptation, Cross-Protection, and Changes in Protein Synthesis. Applied and Environmental Microbiology, 1997, 63 (2), pp.812-814. ⟨hal-02187958⟩