Polymorphic forms of fasidotril, their methods of preparation and pharmaceutical compositions comprising them

Marc Capet , Gérard Coquerel (1) , Denis Danvy , Jeanne-Marie Lecomte , Marie-Noëlle Petit (1) , Jean-Charles Schwartz

1 SMS - Sciences et Méthodes Séparatives

The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylpropionyl-amino)propionate, hereinafter called Fasidotril, their methods of preparation and novel pharmaceutical compositions containing them.

Domaines: Matériaux; Cristallographie; Chimie organique

Marc Capet, Gérard Coquerel, Denis Danvy, Jeanne-Marie Lecomte, Marie-Noëlle Petit, et al.. Polymorphic forms of fasidotril, their methods of preparation and pharmaceutical compositions comprising them. France, Patent n° : US20030203965A1. 2005. ⟨hal-01949838⟩