Method for the preparation of (3s,3s') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid)

Fabrice Balavoine , Jonathan Madec , Jean-Marie Schneider , Gérard Coquerel (1) , Nicolas Couvrat (1) , Yohann Cartigny (1) , Marie-Noëlle Petit (1)

1 SMS - Sciences et Méthodes Séparatives

The present invention relates to a new method for the preparation of (3S,3S') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.

Domains: Material chemistry; Cristallography; Organic chemistry

Fabrice Balavoine, Jonathan Madec, Jean-Marie Schneider, Gérard Coquerel, Nicolas Couvrat, et al.. Method for the preparation of (3s,3s') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid). France, Patent n° : WO2012045849A1. 2011. ⟨hal-01949490⟩