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Etude des adaptations du métabolisme protéique, en particulier, énergétique et oxydatif, en réponse à des changements physiologiques ou environnementaux : approche ciblée et approche globale

Abstract : The present work has been conducted in a double ecotoxicological and metabolic context. The aim was to study protein modifications linked to chemical or physical disorders in order to highlight the molecular and physiological mechanisms of stress responses. Ultimately, this work is part of the search in tools for environmental diagnostics. Studied species are common sentinels in environmental monitoring, mainly marine and freshwater bivalves. Two approaches have been developed: an open approach based on the establishment and comparison of proteomic fingerprints; a targeted approach focused on enzymatic markers involved in stress response. Special attention was paid to the superoxide dismutase enzyme, which has been used as a new tool for discrimination of two neighboring species of dreissena.
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https://hal-normandie-univ.archives-ouvertes.fr/tel-01963849
Contributor : Béatrice Rocher <>
Submitted on : Saturday, January 19, 2019 - 9:58:21 AM
Last modification on : Wednesday, March 27, 2019 - 10:58:04 AM

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  • HAL Id : tel-01963849, version 1

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Béatrice Rocher. Etude des adaptations du métabolisme protéique, en particulier, énergétique et oxydatif, en réponse à des changements physiologiques ou environnementaux : approche ciblée et approche globale. Ecotoxicologie. ULH-Normandie Université, 2017. ⟨tel-01963849⟩

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