Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in Pseudomonas aeruginosa

Damien Tortuel (1) , Ali Tahrioui (1) , Audrey David (1) , Mélyssa Cambronel (1) , Flore Nilly (1) , Thomas Clamens (1) , Olivier Maillot (1) , Magalie Barreau (1) , Marc Feuilloley (1) , Olivier Lesouhaitier (1) , Alain Filloux , Emeline Bouffartigues (1) , Pierre Cornelis , Sylvie Chevalier (1)

1 CBSA - Communication Bactérienne et Stratégies Anti-infectieuses

Filamentous bacteriophages can become superinfective and infect P. aeruginosa , even though they are inserted in the genome as lysogens. Despite this productive infection, growth of the host is only mildly affected, allowing the study of the interaction between the phage and the host, which is not possible in the case of lytic phages killing rapidly their host.

Domains: Life Sciences [q-bio]

Damien Tortuel, Ali Tahrioui, Audrey David, Mélyssa Cambronel, Flore Nilly, et al.. Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in Pseudomonas aeruginosa. Microbiology Spectrum, 2022, 10 (5), pp.1788. ⟨10.1128/spectrum.01548-22⟩. ⟨hal-03890330⟩