Skip to Main content Skip to Navigation
New interface
Journal articles

Nanoscale control of oxides by laser ablation: design and applications

Abstract : Abstract While metal oxides synthesized as thin films have attracted much attention due to their electronic applications, we show here that they can also be used as bio-surfaces for the growth of stem cells, a field of research which has not been much explored. To demonstrate this, thin films (150–200 Å) of titanium oxide (TiO 2 ) and aluminum oxide (Al 2 O 3 ) were deposited on glass using the pulsed laser deposition technique and mesenchymal stem cells were grown on these layers. Cell behavior was evaluated with respect to various key parameters, such as the composition, wettability, morphology and thickness of the films. Our results indicate that thin films of TiO 2 and Al 2 O 3 can not only support stem cell adhesion and growth, but can be used to influence the osteogenic and chondrogenic differentiation paths, which opens the route for a variety of novel biocompatible materials.
Document type :
Journal articles
Complete list of metadata

https://hal-normandie-univ.archives-ouvertes.fr/hal-03541356
Contributor : Wilfrid Prellier Connect in order to contact the contributor
Submitted on : Monday, January 24, 2022 - 3:38:42 PM
Last modification on : Saturday, June 25, 2022 - 9:57:27 AM

Identifiers

Citation

Wilfrid Prellier, M. Singh, M Khokhlova, M Hammad, E Lhuissier, et al.. Nanoscale control of oxides by laser ablation: design and applications. Journal of Physics D: Applied Physics, 2021, 54 (23), pp.61951O. ⟨10.1117/12.668243⟩. ⟨hal-03541356⟩

Share

Metrics

Record views

32