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Preparation, characterization and antibacterial applications of ZnAl-LDH with the diaminododecylphosphonic acid intercalation

Abstract : Layered double hydroxides (LDHs) have been widely investigated in a wide range of applications in health, in the pharmaceutical industry and in the material of biotechnology industries. This material can be considered as a group of promising materials in the development of new health applications. The combination of phosphonic acid with LDHs material create a new hybrid material with new properties.In this work the synthesis of Zn/Al double layered hydroxides by chemical co-precipitation method (molar ration 2) and grafted with Diamino Dodecyl Phosphonic Acid (DDPA) via anion-exchange mechanism. The samples were characterized and confirmed by X-ray diffraction (XRD), and the presence of diamino dodecyl phosphonic acid (DDPA) was verified by Elemental analysis, BET analysis, and infrared spectroscopy. Both of the samples were found to be showing antibacterial activity. The zone diameters of Zn-Al-LDH were 40 mm and 25 mm for Escherichia coli(ATCC 25922) and Streptococcus (ATCC 25922)and 20 mm for bacillus (ATCC 25922) whereas the same for hybrid LDH (Zn-Al-DDPA) were43 mm , 32 mm and 25 mm for the same bacteria showing stronger antibacterial activity of the grafted material over the material itself. The experimental results confirm the application of Zn-Al-DDPA in the field of antibacterial activities and may offer a promising antibacterial elucidation to the society. doi: 10.38150/sajeb.11(5).p600-604429.
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Submitted on : Tuesday, January 4, 2022 - 2:59:16 PM
Last modification on : Saturday, June 25, 2022 - 9:57:26 AM

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Ziani Hanane, M 'Hamed Kaid, Ikhou Djamila, Abdelkader Ammam, Didier Villemin. Preparation, characterization and antibacterial applications of ZnAl-LDH with the diaminododecylphosphonic acid intercalation. South Asian Journal of Experimental Biology, Horizon Publisher India, 2021, 11 (5), pp.600-604. ⟨hal-03510457⟩

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