Pharmacokinetic modeling of morphine and its glucuronides: Comparison of nebulization versus intravenous route in healthy volunteers

Thomas Duflot (1, 2, 3) , Tony Pereira (2) , Marie‐pierre Tavolacci (4, 5, 6, 3) , Robinson Joannidès (1, 2, 3) , Frédéric Aubrun (7) , Fabien Lamoureux (1, 2, 3) , Virginie Eve Lvovschi (4, 5, 2, 3)

1 EnVI - Endothélium, valvulopathies et insuffisance cardiaque
2 CHU Rouen
3 UNIROUEN UFR Santé - UNIROUEN - UFR Santé
4 ADEN - Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau
5 IRIB - Institute for Research and Innovation in Biomedicine
6 CIC Rouen - Centre d'Investigation Clinique [CHU Rouen]
7 Hôpital de la Croix-Rousse [CHU - HCL]

Domains: Life Sciences [q-bio]; Human health and pathology; Tissues and Organs [q-bio.TO]

Thomas Duflot, Tony Pereira, Marie‐pierre Tavolacci, Robinson Joannidès, Frédéric Aubrun, et al.. Pharmacokinetic modeling of morphine and its glucuronides: Comparison of nebulization versus intravenous route in healthy volunteers. CPT: Pharmacometrics and Systems Pharmacology, 2021, ⟨10.1002/psp4.12735⟩. ⟨hal-03483329⟩