Skip to Main content Skip to Navigation
Journal articles

First report of mycophenolic acid production by Eurotium repens isolated from agricultural and indoor environments

Abstract : Mycophenolic acid is considered as an immunosuppressive pharmaceutical drug, but also as a mycotoxin due to its undesirable presence in various feedstuffs. Although Penicillium brevicompactum has been historically identified as the major producer of mycophenolic acid, this study reports for the first time the production of mycophenolic acid by isolates of Eurotium repens collected from agricultural and indoor environments. Fungal identification was achieved by scanning electron microscopy and molecular techniques, and mycophenolic acid production was confirmed by two analytical methods (gas and liquid chromatography coupled to mass spectrometry). These findings suggest that mycophenolic acid production and immunosuppressive properties of other closely related Eurotium should be evaluated in future studies.
Document type :
Journal articles
Complete list of metadata

https://hal-normandie-univ.archives-ouvertes.fr/hal-03428788
Contributor : Margot BEGUE Connect in order to contact the contributor
Submitted on : Monday, November 15, 2021 - 12:00:18 PM
Last modification on : Thursday, March 3, 2022 - 3:41:25 AM

Identifiers

Collections

Citation

V. Séguin, S. Gente, N. Heutte, P. Vérité, Valérie Kientz-Bouchart, et al.. First report of mycophenolic acid production by Eurotium repens isolated from agricultural and indoor environments. World Mycotoxin Journal, 2014, 7 (3), pp.321-328. ⟨10.3920/WMJ2013.1619⟩. ⟨hal-03428788⟩

Share

Metrics

Record views

10