Influence of Glutamine and Branched-Chain Amino Acids Supplementation during Refeeding in Activity-Based Anorectic Mice.

Clément L'Huillier (1, 2, 3) , Marine Jarbeau (1, 2, 3) , Floriane Pingeon (1, 2, 3) , Wafa Bahlouli (1, 2, 3) , Emmeline Salameh (1, 2, 3) , Asma Amamou (1, 2, 3) , Alexis Goichon (1, 2, 3) , Pauline Tirelle (1, 2, 3) , Jean-Luc Do Rego (4, 2, 3) , Pierre Déchelotte (1, 2, 3, 5) , Moïse Coëffier (1, 2, 3, 5)

1 ADEN - Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau
2 IRIB - Institute for Research and Innovation in Biomedicine
3 UNIROUEN UFR Santé - UNIROUEN - UFR Santé
4 SCAC - Service Commun d'Analyse Comportementale
5 Service de nutrition [CHU Rouen]

Optimizing the refeeding of patients with anorexia nervosa remains important to limit somatic complications of malnutrition, as well as to avoid disease relapses by targeting persistent mood and intestinal disorders. We aimed to evaluate the effects of glutamine (Gln) and branched-chain amino acids (BCAA) supplementation during refeeding in activity-based anorectic (ABA) mice.

Keywords: activity-based anorexia; branched-chain amino acids; colon; glutamine; protein synthesis; refeeding

Domains: Life Sciences [q-bio]; Food and Nutrition

Clément L'Huillier, Marine Jarbeau, Floriane Pingeon, Wafa Bahlouli, Emmeline Salameh, et al.. Influence of Glutamine and Branched-Chain Amino Acids Supplementation during Refeeding in Activity-Based Anorectic Mice.. Nutrients, 2020, 12 (11), ⟨10.3390/nu12113510⟩. ⟨hal-03023043⟩