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Journal articles
Phenysilane and Silicon Tetraacetate: Versatile Promotors for Amide Synthesis
Abstract : Phenylsilane was reevaluated as a useful coupling reagent for amide synthesis. At room temperature, a wide range of amides and peptides were obtained in good to excellent yields (up to 99%). For the first time, Weinreb amides synthesis mediated by a hydrosilane were also documented. Comparative experiments with various acetoxysilanes suggested the involvement of a phenyl-triacyloxysilane. From this mechanistic study, silicon tetracetate was shown as an efficient amine acylating agent.
Cited literature [30 references]
https://hal-normandie-univ.archives-ouvertes.fr/hal-02962274
Contributor : Jérôme Blanchet Connect in order to contact the contributor
Submitted on : Friday, October 9, 2020 - 9:55:15 AM
Last modification on : Wednesday, November 3, 2021 - 5:24:40 AM
Long-term archiving on: : Sunday, January 10, 2021 - 6:18:40 PM
Contributor : Jérôme Blanchet Connect in order to contact the contributor
Submitted on : Friday, October 9, 2020 - 9:55:15 AM
Last modification on : Wednesday, November 3, 2021 - 5:24:40 AM
Long-term archiving on: : Sunday, January 10, 2021 - 6:18:40 PM
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Morisset manuscript final.pdf
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