Extension to the SCF2H , SCH2F , and SCF2R Motifs (R = PO (OEt )2, CO2R , Rf )

Tatiana Besset (1) , Thomas Poisson (1)

1 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse

In the past decade, tremendous advances have been made regarding the development of new sulfur‐containing fluorinated groups. Indeed, the quest for original fluorinated residues and especially those bearing a functional group that can be either modulated or directly used in drug discovery program is appealing. Among them, a strong interest was dedicated to SCF2H, SCH2F, and SCF2FG motifs (FG = functional group). In this chapter, we have summarized the recent progress made in that research field to access to SCF2H, SCH2F, SCF2PO(OEt)2, SCF2CO2R, and SRf.

Domaines: Chimie

Tatiana Besset, Thomas Poisson. Extension to the SCF2H , SCH2F , and SCF2R Motifs (R = PO (OEt )2, CO2R , Rf ). Emerging Fluorinated Motifs : Synthesis, Properties, and Applications, Wiley-VCH, pp.449-475, 2020, 978-3-527-82434-2 (oBook). - 978-3-527-82432-8 (ePDF). - 978-3-527-82433-5 (ePub). ⟨10.1002/9783527824342.ch16⟩. ⟨hal-02885856⟩