New strategy for the construction of a pyrroloisoquinolinone scaffold and application to the synthesis of topoisomerase-I inhibitors

Adam Daïch (1) , Frederic Pin (1) , Sébastien Comesse (1)

1 URCOM - Unité de Recherche en Chimie Organique et Macromoléculaire

Domains: Chemical Sciences; Catalysis; Chemical Sciences; Organic chemistry; Chemical Sciences; Medicinal Chemistry

Adam Daïch, Frederic Pin, Sébastien Comesse. New strategy for the construction of a pyrroloisoquinolinone scaffold and application to the synthesis of topoisomerase-I inhibitors. Drug Discovery and Selection. International Conference on Medicinal Chemistry/45èmes Rencontres Internationales de Chimie Thérapeutique), Jun 2009, Orléans, France. ⟨hal-02568174⟩