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Journal articles
Pd(0)-Catalyzed Direct Inter- and Intramolecular C–H Functionalization of 4-Carboxyimidazoles
Abstract : The palladium-catalyzed arylation and alkenylation of N-substituted methyl imidazole-4-carboxylates are described through inter- and intramolecular pathways. Both direct C2–H and C5–H arylation and alkenylation proceed under Pd(0)/Cu(I) cooperative catalysis and Pd(0) catalysis, respectively, in low-polarity 1,4-dioxane solvent. The methodology gives access to C2 (hetero)aryl or alkenyl imidazoles as well as innovative C2- and C5-arylated fused imidazoles tricycles with a five- to seven-membered middle ring.
https://hal-normandie-univ.archives-ouvertes.fr/hal-02548986
Contributor : Madeleine Roux-Merlin Connect in order to contact the contributor
Submitted on : Tuesday, December 1, 2020 - 2:28:22 PM
Last modification on : Tuesday, January 4, 2022 - 6:00:48 AM
Long-term archiving on: : Tuesday, March 2, 2021 - 7:27:14 PM
Contributor : Madeleine Roux-Merlin Connect in order to contact the contributor
Submitted on : Tuesday, December 1, 2020 - 2:28:22 PM
Last modification on : Tuesday, January 4, 2022 - 6:00:48 AM
Long-term archiving on: : Tuesday, March 2, 2021 - 7:27:14 PM
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