Synthesis of Various Terphenyl Derivatives; Study of a New Amine Receptor with a Terphenyl Structure

Patricia Le Nahenec-Martel (1) , Stéphane Leleu (1) , Francis Marsais (1) , Cyril Papamicaël (1) , Vincent Levacher (1) , Georges Dupas (1)

1 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse

The synthesis of functionalized terphenyl derivatives was achieved starting from readily available 1,3-dichloro-2-iodobenzene. Among the prepared compounds, a molecule able to bind with benzylamine is described. This new host consist in a terphenyl structure possessing two side arms with aminomethylpyridines moieties. An interesting association constant with benzylamine and an unexpected 2/1 (host/guest) complex have been determined by using 1H NMR dilution experiments.

Domains: Chemical Sciences

Patricia Le Nahenec-Martel, Stéphane Leleu, Francis Marsais, Cyril Papamicaël, Vincent Levacher, et al.. Synthesis of Various Terphenyl Derivatives; Study of a New Amine Receptor with a Terphenyl Structure. Letters in Organic Chemistry, 2005, 2 (2), pp.172-175. ⟨10.2174/1570178053202955⟩. ⟨hal-02547629⟩