Enantioselective catalytic synthesis of α-aryl-α-SCF 3 -β 2,2 -amino acids - Archive ouverte HAL Access content directly
Journal Articles Organic & Biomolecular Chemistry Year : 2020

Enantioselective catalytic synthesis of α-aryl-α-SCF 3 -β 2,2 -amino acids

(1) , (2) , (2) , (1)
1
2

Abstract

We herein report a novel entry towards chiral α-SCF3-β2,2-amino acids by carrying out the ammonium salt-catalyzed α-trifluoromethylthiolation of isoxazolidin-5-ones. This approach allowed for high enantioselectivities and high yields and the obtained heterocycles proved to be versatile platforms to access other targets of potential interest.
Fichier principal
Vignette du fichier
OBC2020(Autriche)_Accepted Manuscript.pdf (1.35 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-02442629 , version 1 (27-02-2020)

Identifiers

Cite

Andreas Eitzinger, Jean-François Brière, Dominique Cahard, Mario Waser. Enantioselective catalytic synthesis of α-aryl-α-SCF 3 -β 2,2 -amino acids. Organic & Biomolecular Chemistry, 2020, 18 (3), pp.405-408. ⟨10.1039/c9ob02666e⟩. ⟨hal-02442629⟩
85 View
42 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More