Efficient Conversion of Epoxides into Carbonates with CO2 and a Single Organocatalyst: Laboratory and Kilogram-Scale Experiments

Rabah Azzouz (1) , Viviana Contreras Moreno (2) , Clara Herasme-Grullon (2) , Vincent Levacher (1) , Lionel Estel (2) , Alain Ledoux (2) , Salim Derrouiche (3) , Francis Marsais (4) , Laurent Bischoff (1)

1 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse
2 LSPC - Laboratoire de Sécurité des Procédés Chimiques
3 VeRI - Veolia Recherche & Innovation
4 VFP Therapies Drugs : Highway to the Brain

Cheap and readily-available 2-aminopyridine and related compounds can be used as organocatalysts for the conversion of epoxides into cyclic carbonates. This reaction gives high conversions under solvent-free conditions, and is amenable to a kilogram-scale under mild conditions.

Mots clés: aminopyridine; organocatalysis; cyclic carbonates; carbon dioxide; epoxides epoxides; pyridines; organocatalyst; cyclic carbonate

Domaines: Génie chimique

Rabah Azzouz, Viviana Contreras Moreno, Clara Herasme-Grullon, Vincent Levacher, Lionel Estel, et al.. Efficient Conversion of Epoxides into Carbonates with CO2 and a Single Organocatalyst: Laboratory and Kilogram-Scale Experiments. SYNLETT, 2020, 31 (02), pp.183-188. ⟨10.1055/s-0039-1691405⟩. ⟨hal-02958227⟩