Action of x-rays on mammalian cells, J. Exp. Med, vol.103, pp.653-666, 1956. ,
A survival curve for mammalian cells irradiated in vivo, Nature, vol.183, pp.1060-1061, 1959. ,
The linear-quadratic model is an appropriate methodology for determining isoeffective doses at large doses per fraction, Semin. Radiat. Oncol, vol.18, pp.234-239, 2008. ,
Conservative treatment of uveal melanoma: Local recurrence after proton beam therapy, Int. J. Radiat. Oncol. Biol. Phys, vol.17, pp.493-498, 1989. ,
The risk of enucleation after proton beam irradiation of uveal melanoma, Ophthalmology, vol.96, pp.1377-1383, 1989. ,
Proton radiation therapy for chordomas and chondrosarcomas of the skull base, J. Neurosurg, vol.91, pp.432-439, 1999. ,
Combination of photon and proton radiation therapy for chordomas and chondrosarcomas of the skull base: The Centre de Protonthérapie D'Orsay experience, Int. J. Radiat. Oncol. Biol. Phys, vol.51, pp.392-398, 2001. ,
Accelerated fractionated proton/photon irradiation to 90 cobalt gray equivalent for glioblastoma multiforme: Results of a phase II prospective trial, J. Neurosurg, vol.91, pp.251-260, 1999. ,
Long-term survival after treatment of glioblastoma multiforme with hyperfractionated concomitant boost proton beam therapy, Pract. Radiat. Oncol, vol.5, pp.9-16, 2015. ,
Proton therapy-Present and future, Adv. Drug Deliv. Rev, vol.109, pp.26-44, 2017. ,
Imaging Changes in Pediatric Intracranial Ependymoma Patients Treated With Proton Beam Radiation Therapy Compared to Intensity Modulated Radiation Therapy, Int. J. Radiat. Oncol. Biol. Phys, vol.93, pp.54-63, 2015. ,
Proton Relative Biological Effectiveness-Uncertainties and Opportunities, Int. J. Part. Ther, vol.5, pp.2-14, 2018. ,
Dose painting with IMPT, helical tomotherapy and IMXT: A dosimetric comparison, Radiother. Oncol, vol.86, pp.30-34, 2008. ,
Proton beam therapy for locally advanced lung cancer: A review, World J. Clin. Oncol, vol.5, pp.568-575, 2014. ,
Definitive proton radiation therapy and concurrent cisplatin for unresectable head and neck adenoid cystic carcinoma: A series of 9 cases and a critical review of the literature, Head Neck, vol.38, 2016. ,
Particle therapy and nanomedicine: State of art and research perspectives, Cancer Nanotechnol, vol.8, issue.9, 2017. ,
Clinical development of new drug-radiotherapy combinations, Nat. Rev. Clin. Oncol, vol.13, pp.627-642, 2016. ,
Proton beam therapy and immunotherapy: An emerging partnership for immune activation in non-small cell lung cancer, Transl. Lung Cancer Res, vol.7, pp.180-188, 2018. ,
The impact of hypoxia and its modification of the outcome of radiotherapy, J. Radiat. Res, vol.57, pp.90-98, 2016. ,
Different mechanisms of cell death in radiosensitive and radioresistant p53 mutated head and neck squamous cell carcinoma cell lines exposed to carbon ions and x-rays, Int. J. Radiat. Oncol. Biol. Phys, vol.74, pp.200-209, 2009. ,
URL : https://hal.archives-ouvertes.fr/in2p3-00382723
Telomere profiling: Toward glioblastoma personalized medicine, Mol. Neurobiol, vol.47, pp.64-76, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00830922
Impact of therapeutic irradiation on healthy articular cartilage, Radiat. Res, vol.183, pp.135-146, 2015. ,
URL : https://hal.archives-ouvertes.fr/cea-01938044
Differential pattern of HIF-1? expression in HNSCC cancer stem cells after carbon ion or photon irradiation: One molecular explanation of the oxygen effect, Br. J. Cancer, vol.116, pp.1340-1349, 2017. ,
URL : https://hal.archives-ouvertes.fr/cea-01938093
Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation, J. Radiat. Res, vol.60, pp.69-79, 2019. ,
Radiation-enhanced cell migration/invasion process: A review, Crit. Rev. Oncol. Hematol, vol.92, pp.133-142, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01016897
Cancer Stem Cells: A Review from Origin to Therapeutic Implications, p.17, 2019. ,
Carbon ion irradiation withstands cancer stem cells' migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC), Oncotarget, vol.7, pp.47738-47749, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01375896
Kill painting of hypoxic tumors with multiple ion beams, Phys. Med. Biol, vol.64, p.45008, 2019. ,
Ultrahigh dose-rate, "flash" irradiation minimizes the side-effects of radiotherapy, Cancer Radiother, vol.19, pp.526-531, 2015. ,
Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice, Sci. Transl. Med, vol.6, 2014. ,
Biological effects in normal cells exposed to FLASH dose rate protons, Radiother. Oncol, vol.139, pp.51-55, 2019. ,
Hypoxia in cancer: Significance and impact on clinical outcome, Cancer Metastasis Rev, vol.26, pp.225-239, 2007. ,
RBE and OER within the spread-out Bragg peak for proton beam therapy: In vitro study at the Proton Medical Research Center at the University of Tsukuba, J. Radiat. Res, vol.55, pp.1028-1032, 2014. ,
Modelling of the oxygen enhancement ratio for ion beam radiation therapy, Phys. Med. Biol, vol.56, pp.3251-3268, 2011. ,
Dose or "LET" painting-What is optimal in particle therapy of hypoxic tumors?, Acta Oncol, vol.54, pp.1614-1622, 2015. ,
Radiobiology for the Radiologist ,
, , 2006.
Inactivation of aerobic and hypoxic cells from three different cell lines by accelerated (3)He-, (12)Cand (20)Ne-ion beams, Radiat. Res, vol.154, pp.485-496, 2000. ,
Clinical oxygen enhancement ratio of tumors in carbon ion radiotherapy: The influence of local oxygenation changes, J. Radiat. Res, vol.55, pp.902-911, 2014. ,
Bringing the heavy: Carbon ion therapy in the radiobiological and clinical context, Radiat. Oncol, vol.88, issue.9, 2014. ,
Radiobiology for the Radiologist ,
, , 2012.
Differences in the kinetics of gamma-H2AX fluorescence decay after exposure to low and high LET radiation, Int. J. Radiat. Biol, vol.86, pp.682-691, 2010. ,
The complexity of DNA damage: Relevance to biological consequences, Int. J. Radiat. Biol, vol.66, pp.427-432, 1994. ,
A multiple-radical model for radiation action on DNA and the dependence of OER on LET, Int. J. Radiat. Biol, vol.69, pp.351-358, 1996. ,
Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications, Radiat. Oncol, 2011. ,
High-LET ion radiolysis of water: Oxygen production in tracks, Radiat. Res, vol.171, pp.379-386, 2009. ,
Primary production of oxygen from irradiated water as an explanation for decreased radiobiological oxygen enhancement at high LET, Nature, vol.260, pp.316-318, 1976. ,
How can we overcome tumor hypoxia in radiation therapy?, J. Radiat. Res, vol.52, pp.545-556, 2011. ,
Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy, Clin. Cancer Res, vol.18, pp.5585-5594, 2012. ,
Carbon ion radiotherapy of human lung cancer attenuates HIF-1 signaling and acts with considerably enhanced therapeutic efficiency, FASEB J, vol.28, pp.1412-1421, 2014. ,
ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion, Cancers ,
URL : https://hal.archives-ouvertes.fr/hal-02124279
Enhancing tumor radiosensitivity by intracellular delivery of survivin antagonists, vol.68, pp.1056-1058, 2007. ,
Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe, Oncotarget, vol.6, pp.2101-2119, 2015. ,
Proton vs carbon ion beams in the definitive radiation treatment of cancer patients, Radiother. Oncol, vol.95, pp.3-22, 2010. ,
Accurate description of the cell survival and biological effect at low and high doses and LET's, J. Radiat. Res, vol.52, pp.389-407, 2011. ,
Cancer-related inflammation, Nature, vol.454, pp.436-444, 2008. ,
Hallmarks of Cancer: The Next Generation, Cell, vol.144, pp.646-674, 2011. ,
The immune contexture in human tumours: Impact on clinical outcome, Nat. Rev. Cancer, vol.12, pp.298-306, 2012. ,
Innate immunity in vertebrates: An overview, Immunology, vol.148, pp.125-139, 2016. ,
Alternative activation of tumor-associated macrophages by IL-4: Priming for protumoral functions, Cell Cycle, vol.9, pp.4824-4835, 2010. ,
Tumor-associated macrophages in glioma: Friend or foe?, J. Oncol, vol.486912, 2013. ,
Expression of M2-polarized macrophages is associated with poor prognosis for advanced epithelial ovarian cancer, Technol. Cancer Res. Treat, vol.12, pp.259-267, 2013. ,
Prognostic significance of tumor-associated macrophages in breast cancer: A meta-analysis of the literature, Oncotarget, vol.8, pp.30576-30586, 2017. ,
Modulation of intercellular communication mediated at the cell surface and on extracellular, plasma membrane-derived vesicles by ionizing radiation, Exp. Hematol, vol.31, pp.455-464, 2003. ,
Expression of NF-?B p50 in tumor stroma limits the control of tumors by radiation therapy, PLoS ONE, vol.7, 2012. ,
Irradiation promotes an m2 macrophage phenotype in tumor hypoxia. Front, Oncol, vol.2, p.89, 2012. ,
M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma, Oncotarget, vol.8, pp.72597-72612, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02100869
Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities ,
Alterations of immune functions induced by 12C6+ ion irradiation in mice, Int. J. Radiat. Biol, vol.83, pp.577-581, 2007. ,
Carbon Ion Irradiated Neural Injury Induced the Peripheral Immune Effects in Vitro or in Vivo, Int. J. Mol. Sci, vol.16, pp.28334-28346, 2015. ,
Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma, Oncotarget, vol.10, pp.633-646, 2018. ,
Peripheral lymphocyte subset variation predicts prostate cancer carbon ion radiotherapy outcomes, Oncotarget, vol.7, pp.26422-26435, 2016. ,
Differential effects of irradiation with carbon ions and x-rays on macrophage function, J. Radiat. Res, vol.50, pp.223-231, 2009. ,
Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche, JCI Insight, vol.4, 2019. ,
Bystander effects and radiotherapy, Rep. Pract. Oncol. Radiother, vol.20, pp.12-21, 2015. ,
Radiation-induced bystander effects: Past history and future directions, Radiat. Res, vol.155, pp.759-767, 2001. ,
Radiation-induced bystander and systemic effects serve as a unifying model system for genotoxic stress responses, Mutat. Res, vol.778, pp.13-22, 2018. ,
Proteomic overview and perspectives of the radiation-induced bystander effects, Mutat. Res. Rev. Mutat. Res, vol.763, pp.280-293, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-02503001
Radiation-induced bystander signalling in cancer therapy, Nat. Rev. Cancer, vol.9, pp.351-360, 2009. ,
Targeted cytoplasmic irradiation induces bystander responses, Proc. Natl. Acad. Sci, vol.101, pp.13495-13500, 2004. ,
Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from alpha-particle-irradiated normal human fibroblast cultures, Cancer Res, vol.62, pp.5436-5442, 2002. ,
Bystander signaling between glioma cells and fibroblasts targeted with counted particles, Int. J. Cancer, vol.116, pp.45-51, 2005. ,
Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis, Br. J. Cancer, vol.83, pp.1223-1230, 2000. ,
A reaction-diffusion model for radiation-induced bystander effects, J. Math. Biol, vol.75, pp.341-372, 2017. ,
Bystander effects and their implications for clinical radiation therapy: Insights from multiscale in silico experiments, J. Theor. Biol, vol.401, pp.1-14, 2016. ,
Bystander effects and their implications for clinical radiotherapy, J. Radiol. Prot, vol.29, pp.133-142, 2009. ,
Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes, J. Cell Commun. Signal, vol.13, pp.343-356, 2019. ,
URL : https://hal.archives-ouvertes.fr/inserm-02125509
Radiotherapy: Basic Concepts and Recent Advances, Med. J. Armed Forces India, vol.66, pp.158-162, 2010. ,
Both irradiated and bystander effects link with DNA repair capacity and the linear energy transfer, Life Sci, vol.222, pp.228-234, 2019. ,
Long-term consequences of radiation-induced bystander effects depend on radiation quality and dose and correlate with oxidative stress, Radiat. Res, vol.175, pp.405-415, 2011. ,
Implications of Intercellular Signaling for Radiation Therapy: A Theoretical Dose-Planning Study, Int. J. Radiat. Oncol. Biol. Phys, vol.87, pp.1148-1154, 2013. ,
Radiation-induced bystander effects: What are they, and how relevant are they to human radiation exposures?, Radiat. Res, vol.176, pp.139-157, 2011. ,
Proton beam radiation therapy results in significantly reduced toxicity compared with intensity-modulated radiation therapy for head and neck tumors that require ipsilateral radiation, Radiother. Oncol, vol.118, pp.286-292, 2016. ,
Long-term toxic effects of proton radiotherapy for paediatric medulloblastoma: A phase 2 single-arm study, Lancet Oncol, vol.17, pp.287-298, 2016. ,
Incidence of second malignancies among patients treated with proton versus photon radiation, Int. J. Radiat. Oncol. Biol. Phys, vol.87, pp.46-52, 2013. ,
Second nonocular tumors among survivors of retinoblastoma treated with contemporary photon and proton radiotherapy, Cancer, vol.120, pp.126-133, 2014. ,
Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research ,
Working Group for the Bone and Soft Tissue Sarcomas. Carbon ion radiotherapy for localized primary sarcoma of the extremities: Results of a phase I/II trial, Radiother. Oncol, vol.105, pp.226-231, 2012. ,
Dose-volume histogram and dose-surface histogram analysis for skin reactions to carbon ion radiotherapy for bone and soft tissue sarcoma, Radiother. Oncol, vol.95, pp.60-65, 2010. ,
Working Group for Bone and Soft Tissue Sarcomas. Impact of carbon ion radiotherapy for primary spinal sarcoma, Cancer, vol.119, pp.3496-3503, 2013. ,
Working Group for Bone and Soft Tissue Sarcomas. Carbon Ion Radiation Therapy for Unresectable Sacral Chordoma: An Analysis of 188 Cases, Int. J. Radiat. Oncol. Biol. Phys, vol.95, pp.322-327, 2016. ,
Carbon Ion Radiation Therapy for Chondrosarcoma, Int. J. Radiat. Oncol. Biol. Phys, vol.84, 2012. ,
Dose escalation study of carbon ion radiotherapy for locally advanced carcinoma of the uterine cervix, Int. J. Radiat. Oncol. Biol. Phys, vol.65, pp.388-397, 2006. ,
Carbon-ion radiotherapy for locally advanced cervical cancer with bladder invasion, J. Radiat. Res, vol.57, pp.684-690, 2016. ,
Risk of subsequent primary cancers after carbon ion radiotherapy, photon radiotherapy, or surgery for localised prostate cancer: A propensity score-weighted, retrospective, cohort study, Lancet Oncol, vol.20, pp.674-685, 2019. ,
, Biomarkers in Risk Assessment: Validity and Validation; World Health Organization, 2001.
Biomarkers: Potential uses and limitations, NeuroRx, vol.1, pp.182-188, 2004. ,
Biomarkers in molecular medicine: Cancer detection and diagnosis, BioTechniques, vol.38, pp.9-15, 2005. ,
Biomarkers in molecular epidemiology studies for health risk prediction, Mutat. Res, vol.511, pp.73-86, 2002. ,
Ionizing radiation biomarkers for potential use in epidemiological studies, Mutat. Res, vol.751, pp.258-286, 2012. ,
Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes, PLoS ONE, vol.13, 2018. ,
Necrotic death as a cell fate, Genes Dev, vol.20, pp.1-15, 2006. ,
Serum 8-Oxo-dG as a Predictor of Sensitivity and Outcome of Radiotherapy and Chemotherapy of Upper Gastrointestinal Tumours, Oxid. Med. Cell. Longev, 2018. ,
Nrf2 is a potential therapeutic target in radioresistance in human cancer, Crit. Rev. Oncol. Hematol, vol.88, pp.706-715, 2013. ,
The Half-Life of Serum Thymidine Kinase 1 Concentration Is an Important Tool for Monitoring Surgical Response in Patients with Lung Cancer: A Meta-Analysis, Genet. Test. Mol. Biomark, vol.21, pp.471-478, 2017. ,
Thymidine kinase 1 expression in ovarian serous adenocarcinoma is superior to Ki-67: A new prognostic biomarker, Tumour Biol, 2017. ,
Serum TK1 is a more reliable marker than CEA and AFP for cancer screening in a study of 56,286 people, Cancer Biomark, vol.16, pp.529-536, 2016. ,
Targeting the enzymes involved in arachidonic acid metabolism to improve radiotherapy, Cancer Metastasis Rev, vol.37, pp.213-225, 2018. ,
Immunologically augmented cancer treatment using modern radiotherapy, Trends Mol. Med, vol.19, pp.565-582, 2013. ,
Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away, Proc. Natl. Acad. Sci, vol.102, pp.14203-14208, 2005. ,
The impact of radiation therapy on the antitumor immunity: Local effects and systemic consequences, Cancer Lett, vol.356, pp.114-125, 2015. ,
Ceramide signalling and the immune response, Biochim. Biophys. Acta BBA Lipids Lipid Metab, vol.1301, pp.273-287, 1996. ,
Transcriptional response of murine bone marrow cells to total-body carbon-ion irradiation, Mutat. Res. Genet. Toxicol. Environ. Mutagen, vol.839, pp.49-58, 2019. ,
Carbon-ion-induced activation of the NF-?B pathway, Radiat. Res, vol.175, pp.424-431, 2011. ,
Dose-rate effects of protons on in vivo activation of nuclear factor-kappa B and cytokines in mouse bone marrow cells, Radiat. Environ. Biophys, vol.49, pp.405-419, 2010. ,
Increased long-term expression of pentraxin 3 in irradiated human arteries and veins compared to internal controls from free tissue transfers, J. Transl. Med, issue.11, 2013. ,
Unique proteomic signature for radiation sensitive patients; A comparative study between normo-sensitive and radiation sensitive breast cancer patients, Mutat. Res, vol.776, pp.128-135, 2015. ,
Can 8-oxo-dG be used as a predictor for individual radiosensitivity?, Int. J. Radiat. Oncol. Biol. Phys, vol.50, pp.405-410, 2001. ,
Quantitative modelling of DNA damage using Monte Carlo track structure method, Radiat. Environ. Biophys, vol.38, pp.31-38, 1999. ,
Radiation-induced stress response in peripheral blood of breast cancer patients differs between patients with severe acute skin reactions and patients with no side effects to radiotherapy, Mutat. Res, vol.756, pp.152-157, 2013. ,
Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury, Cancer Lett, vol.327, pp.48-60, 2012. ,
Effects of X-irradiation on mitochondrial DNA damage and its supercoiling formation change, vol.11, pp.886-892, 2011. ,
Toxic effects and foundation of proton radiation on the early-life stage of zebrafish development, Chemosphere, pp.302-312, 0200. ,
Extracellular 8-oxo-dG as a sensitive parameter for oxidative stress in vivo and in vitro, Free Radic. Res, vol.39, pp.153-162, 2005. ,
The nucleotide pool is a significant target for oxidative stress. Free Radic, Biol. Med, vol.41, pp.620-626, 2006. ,
Production of early and late nuclear DNA damage and extracellular 8-oxodG in normal human skin fibroblasts after carbon ion irradiation compared to X-rays, Toxicol. In Vitro, vol.52, pp.116-121, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-02181592
8-Hydroxy-2 -deoxyguanosine (8-OH-dG) as a potential survival biomarker in patients with nonsmall-cell lung cancer, Cancer, vol.109, pp.574-580, 2007. ,
Biomarker evidence of DNA oxidation in lung cancer patients: Association of urinary 8-hydroxy-2 -deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment, FEBS Lett, vol.409, pp.287-291, 1997. ,
8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients, Int. J. Cancer, vol.134, pp.376-383, 2014. ,
Urinary 8-hydroxydeoxyguanosine as a marker of oxidative stress induced genetic toxicity in oral cancer patients, Indian J. Dent. Res, vol.26, pp.226-230, 2015. ,
Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy, Front. Pharm, vol.3, p.94, 2012. ,
Towards multidimensional radiotherapy (MD-CRT): Biological imaging and biological conformality, Int. J. Radiat. Oncol. Biol. Phys, vol.47, pp.551-560, 2000. ,
Molecular imaging-based dose painting: A novel paradigm for radiation therapy prescription, Semin. Radiat. Oncol, vol.21, pp.101-110, 2011. ,
Hypoxia Imaging and Adaptive Radiotherapy: A State-of-the-Art Approach in the Management of Glioma, Front. Med ,
Imaging Modalities to Assess Oxygen Status in Glioblastoma, Front. Med ,
URL : https://hal.archives-ouvertes.fr/hal-01587314
)C] methionine positron emission tomography for target delineation in malignant gliomas: Impact on results of carbon ion radiotherapy, Int. J. Radiat. Oncol. Biol. Phys, vol.70, issue.11, pp.515-522, 2008. ,
Carbon ion radiotherapy boost in the treatment of glioblastoma: A randomized phase I/III clinical trial, Cancer Commun ,
, ADP-ribose) polymerases in double-strand break repair: Focus on PARP1, PARP2 and PARP3, vol.329, pp.18-25, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02369965
PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways, Nucleic Acids Res, vol.42, pp.5616-5632, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01065054
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy, Nature, vol.434, pp.917-921, 2005. ,
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase, Nature, vol.434, pp.913-917, 2005. ,
ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets, Semin. Radiat. Oncol, vol.20, pp.274-281, 2010. ,
ADP-ribose)-polymerase inhibitors as radiosensitizers: A systematic review of pre-clinical and clinical human studies, Oncotarget, vol.8, pp.69105-69124, 2017. ,
URL : https://hal.archives-ouvertes.fr/cea-01938036
Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation, Cancer Sci, vol.103, pp.1045-1050, 2012. ,
Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation, Sci. Rep, vol.8, p.3664, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01738585
Sensitization of chondrosarcoma cells with PARP inhibitor and high-LET radiation, J. Bone Oncol, vol.17, 2019. ,
Radiosensitization by PARP inhibition to proton beam irradiation in cancer cells, Biochem. Biophys. Res. Commun, vol.478, pp.234-240, 2016. ,
Characterisation of Deubiquitylating Enzymes in the Cellular Response to High-LET Ionizing Radiation and Complex DNA Damage, Int. J. Radiat. Oncol. Biol. Phys, vol.104, pp.656-665, 2019. ,
Monte Carlo simulations and atomic calculations for Auger processes in biomedical nanotheranostics, J. Phys. Chem. A, vol.113, pp.12364-12369, 2009. ,
Comparison of gadolinium nanoparticles and molecular contrast agents for radiation therapy-enhancement, Med. Phys, vol.44, pp.5949-5960, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01690606
Therapeutic application of metallic nanoparticles combined with particle-induced x-ray emission effect, Nanotechnology, vol.21, p.425102, 2010. ,
NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): A multicentre, phase 2-3, randomised, controlled trial, Lancet Oncol, vol.20, pp.1148-1159, 2019. ,
Treatment of multiple brain metastases using gadolinium nanoparticles and radiotherapy: NANO-RAD, a phase I study protocol, BMJ Open, vol.9, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02381987
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer, N. Engl. J. Med, vol.366, pp.2443-2454, 2012. ,
Radiation effects on antitumor immune responses: Current perspectives and challenges, Adv. Med. Oncol, vol.10, 2018. ,
Tumor Cells Surviving Exposure to Proton or Photon Radiation Share a Common Immunogenic Modulation Signature, Rendering Them More Sensitive to T Cell-Mediated Killing, Int. J. Radiat. Oncol. Biol. Phys, vol.95, pp.120-130, 2016. ,
Field size effects on the risk and severity of treatment-induced lymphopenia in patients undergoing radiation therapy for solid tumors, Adv. Radiat. Oncol, vol.3, pp.512-519, 2018. ,
Lymphocyte-Sparing Effect of Proton Therapy in Patients with Esophageal Cancer Treated with Definitive Chemoradiation, Int. J. Part. Ther, vol.4, pp.23-32, 2018. ,
, This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, © 2019 by the authors. Licensee MDPI