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Journal articles
Strategy for identification of new neuropeptides
N. Chartrel
1
B Braun
F. Collin
2
B Pierreuse
Y Coulouarn
H Tostivint
L Jeandel
M Trabucchi
D. Vieau
3
I Lihrmann
4
M Tonon
Y. Anouar
1
J Conlon
H. Vaudry
4
1
DC2N - Différenciation et communication neuronale et neuroendocrine (Place Emile Blondel Faculté des Sciences et Techniques 76821 Mont-Saint-Aignan Cedex - France)
- UNIROUEN - Université de Rouen Normandie : U982 (1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex - France)
- NU - Normandie Université (Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U982 (101, rue de Tolbiac, 75013 Paris - France)
2
Université de Liège (Place du 20-Août, 7 4000 Liège - Belgium)
3
Laboratoire de Neuroendocrinologie du Développement (Cité Scientifique Bâtiment SN4 59655 Villeneuve d'Ascq - France)
- Université de Lille, Sciences et Technologies (Cité Scientifique - 59655 Villeneuve d'Ascq Cedex - France)
- CNRS - Centre National de la Recherche Scientifique : EA2701 (France)
4
Neuroendocrinologie cellulaire et moléculaire (Universite de Rouen 76821 MONT-SAINT-AIGNAN CEDEX - France)
- UNIROUEN - Université de Rouen Normandie : U413 (1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex - France)
- NU - Normandie Université (Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U413 (101, rue de Tolbiac, 75013 Paris - France)
Abstract : Neuropeptides play a crucial role in cell communication as neurotransmitters, neuromodulators or neurohormones, and are involved in a number of biological activities including neuroendocrine regulations, control of neurovegetative functions, trophic effects and modulation of the immune response. The number of neuropeptides that have been fully characterized so far is rather limited, as compared to the number of precursor proteins that are actually expressed in nerve cells. Owing to the development of powerful analytical and structural identification methods, and the rapid advance in molecular biology techniques, a number of novel neuropeptides have been characterized during the last decade, in both vertebrates and invertebrates. The aim of the present review is to provide a comprehensive coverage of the different approaches which are currently used to identify novel neuropeptides.
Document type :
Journal articles
Domain :
Complete list of metadatas
https://hal-normandie-univ.archives-ouvertes.fr/hal-02427372
Contributor : Isabelle Lihrmann <>
Submitted on : Friday, January 3, 2020 - 3:18:04 PM
Last modification on : Monday, June 1, 2020 - 4:10:04 AM
Contributor : Isabelle Lihrmann <>
Submitted on : Friday, January 3, 2020 - 3:18:04 PM
Last modification on : Monday, June 1, 2020 - 4:10:04 AM
Identifiers
- HAL Id : hal-02427372, version 1
- PUBMED : 9842468
Collections
COMUE-NORMANDIE | UNIROUEN | DC2N | CNRS
Citation
N. Chartrel, B Braun, F. Collin, B Pierreuse, Y Coulouarn, et al.. Strategy for identification of new neuropeptides. Comptes rendus des séances de la Société de biologie et de ses filiales, Société de biologie, 1998, 192 (4), pp.619-38. ⟨hal-02427372⟩
