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Expression of Proopiomelanocortin and Its Cleavage Enzyme Genes in Rana esculenta and Xenopus laevis Gonads

Abstract : Proopiomelanocortin (POMC) is the precursor protein of different hormones and neuropeptides, and the POMC-derived peptides are produced through proteolytic cleavage. Prohormone convertase PC1 and PC2 are enzymes responsible for the cleavage of the POMC prohormone. The coexpression of POMC, PC1, and PC2 genes was previously described in the brain and the pituitary gland of Rana esculenta and Xenopus laevis, but no data are available for the gonad. The present work demonstrates a gonadal POMC convertase gene expression in Rana esculenta and Xenopus laevis.
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https://hal-normandie-univ.archives-ouvertes.fr/hal-02427136
Contributor : Isabelle Lihrmann <>
Submitted on : Friday, January 3, 2020 - 11:58:24 AM
Last modification on : Tuesday, October 13, 2020 - 5:22:02 PM

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M Carotti, M Nabissi, G Mosconi, F Gangnon, I Lihrmann, et al.. Expression of Proopiomelanocortin and Its Cleavage Enzyme Genes in Rana esculenta and Xenopus laevis Gonads. Annals of the New York Academy of Sciences, Wiley, 2005, 1040 (1), pp.261-263. ⟨10.1196/annals.1327.038⟩. ⟨hal-02427136⟩

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