Solution structure of selenoprotein W and NMR analysis of its interaction with 14-3-3 proteins, J Biol Chem, vol.282, pp.37036-37044, 2007. ,
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1, vol.2, p.6 ,
, Proc Natl Acad Sci U S A, vol.95, pp.7659-7663, 1998.
Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death, Free Radic Biol Med, vol.73, pp.328-336, 2014. ,
Glutathione peroxidase 4 is associated with neuromelanin in substantia nigra and dystrophic axons in putamen of Parkinson's brain, Mol Neurodegener, vol.6, issue.8, 2011. ,
Regulation and function of selenoproteins in human disease, Biochem J, vol.422, pp.11-22, 2009. ,
Changes in selenoprotein P in substantia nigra and putamen in Parkinson's disease, J Parkinsons Dis, vol.2, pp.115-126, 2012. ,
Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies, FASEB J, vol.27, pp.2101-2110, 2013. ,
Metabolism of 3-nitrotyrosine induces apoptotic death in dopaminergic cells, J Neurosci, vol.26, pp.6124-6130, 2006. ,
Neurotoxin-based models of Parkinson's disease, Neuroscience, vol.211, pp.51-76, 2012. ,
Axon degeneration in Parkinson's disease, Exp Neurol, vol.246, pp.72-83, 2013. ,
A highly reproducible rotenone model of Parkinson's disease, Neurobiol Dis, vol.34, pp.279-290, 2009. ,
Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease, Biochim Biophys Acta, vol.1362, pp.77-86, 1997. ,
Selenoprotein T deficiency leads to neurodevelopmental abnormalities and hyperactive behavior in mice, Mol Neurobiol, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01783562
Redox imbalance in Parkinson's disease, Biochim Biophys Acta, vol.1780, pp.1362-1367, 2008. ,
The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease, Inflamm Res, vol.58, pp.747-753, 2009. ,
,
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function, Mol Cell Biol, vol.24, pp.9414-9423, 2004. ,
Epidemiology of Parkinson's disease, Lancet Neurol, vol.5, pp.525-535, 2006. ,
Measuring motor coordination in mice, J Vis Exp, vol.75, pp.1-8, 2013. ,
SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family, Biochem J, vol.46, pp.6871-6882, 2007. ,
Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone, Exp Neurol, vol.187, pp.418-429, 2004. ,
Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusion, J Neurochem, vol.109, pp.1469-1482, 2009. ,
Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease, Nat Neurosci, vol.15, pp.1414-1421, 2012. ,
Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion, FASEB J, vol.22, pp.1756-1768, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-01962747
Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors, Genes Dev, vol.24, pp.2517-2530, 2010. ,
Selenium and selenocysteine: roles in cancer, health and development, Trends Biochem Sci, vol.39, pp.112-120, 2014. ,
Role of oxidative stress in Parkinson's disease, Exp Neurobiol, vol.22, pp.11-17, 2013. ,
Biological selectivity and functional aspects of protein tyrosine nitration, Biochem Biophys Res Commun, vol.305, pp.776-783, 2003. ,
Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development, Mol Cell Biol, vol.25, 1980. ,
New insights into the cause of Parkinson's disease, Neurology, vol.42, pp.2241-2250, 1992. ,
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, J Neurosci, vol.20, pp.1-7, 2000. ,
Microglial and astro-2,3,6-tetrahydropyridine (MPTP), Immunopharmacology, vol.39, pp.167-180, 1998. ,
New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements, J Biol Chem, vol.274, pp.33888-33897, 1999. ,
Sep15, a thioredoxin-like selenoprotein, is involved in the unfolded protein response and differentially regulated by adaptive and acute ER stresses, Biochemistry, vol.48, pp.8458-8465, 2009. ,
Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance, Antioxid Redox Signal, vol.18, pp.1165-1207, 2013. ,
, Parkinson's disease. Lancet, vol.373, pp.2055-2066, 2009.
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases, Nature, vol.443, pp.787-795, 2006. ,
Thioredoxin reductase deficiency potentiates oxidative stress, mitochondrial dysfunction and cell death in dopaminergic cells, PLoS One, vol.7, p.50683, 2012. ,
Pathogenesis of Parkinson's disease: dopamine, vesicles and a-synuclein, Nature, vol.3, pp.932-942, 2002. ,
Rat liver thioredoxin and thioredoxin reductase: purification and characterization, Biochemistry, vol.21, pp.6628-6633, 1982. ,
Mitochondria-ros crosstalk in the control of cell death and aging, J Signal Transduct, p.329635, 2012. ,
Missing pieces in the Parkinson's disease puzzle, Nat Med, vol.16, pp.653-661, 2010. ,
The PACAPregulated gene selenoprotein T is abundantly expressed in mouse and human beta-cells and its targeted inactivation impairs glucose tolerance, Endocrinology, vol.154, pp.3796-3806, 2013. ,
Selenium and human health, Lancet, vol.379, pp.1256-1268, 2012. ,
1-Methyl-4-phenylpyridinium (MPP+) but not 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) selectively destroys dopaminergic neurons in cultures of dissociated rat mesencephalic neurons, Neurosci Lett, vol.12, pp.215-220, 1986. ,
Mitochondria in the aetiology and pathogenesis of Parkinson's disease, Lancet Neurol, vol.7, pp.97-109, 2008. ,
Predictive reward signal of dopamine neurons, J Neurophysiol, vol.80, pp.1-27, 1998. ,
Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to coordination defects in mice, Biochem J, vol.462, pp.67-75, 2014. ,
Selenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells, Biochem Cell Biol, vol.87, pp.953-961, 2009. ,
Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis, J Biol Chem, vol.286, pp.42937-42948, 2011. ,
Bacopa monnieri extract offsets rotenone-induced cytotoxicity in dopaminergic cells and oxidative impairments in mice brain, Cell Mol Neurobiol, vol.32, pp.455-465, 2012. ,
The role of thioredoxin reductases in brain development, PLoS One, vol.3, p.1813, 2008. ,
Mitochondrial dysfunction and oxidative stress in Parkinson's disease, Prog Neurobiol, vol.106, pp.17-32, 2013. ,
The PACAP-regulated gene selenoprotein T is highly induced in nervous, endocrine, and metabolic tissues during ontogenetic and regenerative processes, Endocrinology, vol.152, pp.4322-4335, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00682913
Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation, Cell Tissue Res, vol.318, pp.149-161, 2004. ,
Parkinson's disease, Hum Mol Genet, vol.2, pp.183-194, 2007. ,
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety, Nat Genet, vol.23, pp.99-103, 1999. ,
Neurodegeneration in mice resulting from loss of fonctional selenoprotein P or its receptor apolipoprotein E receptor 2, J Neuropathol Exp Neurol, vol.67, pp.68-77, 2008. ,
Dysfunctions in dopamine systems and ADHD: evidence from animals and modeling, Neural Plast, vol.11, pp.97-114, 2004. ,
Address correspondence to: Dr. Youssef Anouar Laboratory of Neuronal and Neuroendocrine Differentiation and Communication Inserm U982, FASEB J, vol.24, pp.844-852, 2010. ,
, France E-mail: youssef.anouar@univ-rouen.fr Date of first submission to ARS Central, 2015.
Protein-protein interactions of ER-resident selenoproteins with their physiological partners, Biochimie, vol.171, issue.172, pp.197-204, 2020. ,
Selenium: Tracing Another Essential Element of Ferroptotic Cell Death, Cell Chemical Biology, vol.27, pp.409-419, 2020. ,
Common modifications of selenocysteine in selenoproteins, Essays in Biochemistry, vol.64, issue.1, pp.45-53, 2020. ,
Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease, Neurobiology of Disease, vol.134, 2020. ,
Tolerance to Selenoprotein Loss Differs between Human and Mouse, Molecular Biology and Evolution, vol.37, issue.2, pp.341-354, 2020. ,
Selenium speciation analysis in the cerebrospinal fluid of patients with Parkinson's disease, Journal of Trace Elements in Medicine and Biology, vol.57, 2020. ,
,
, Selenoprotein T Promotes Proliferation and G1-to-S Transition in SK-N-SH Cells: Implications in Parkinson's Disease, vol.149, pp.2110-2119
Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins, Free Radical Biology and Medicine, vol.143, pp.573-593, 2019. ,
Progress in the emerging role of selenoproteins in cardiovascular disease: focus on endoplasmic reticulum-resident selenoproteins, Cellular and Molecular Life Sciences, vol.76, issue.20, pp.3969-3985, 2019. ,
Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis. Frontiers in Oncology 9, 2019. ,
AMPK Activation of PGC-1?/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress, Molecular Neurobiology, vol.56, issue.6, pp.4086-4101, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02093045
Prioritized brain selenium retention and selenoprotein expression: Nutritional insights into Parkinson's disease, Mechanisms of Ageing and Development, vol.180, pp.89-96, 2019. ,
Degradation of selenoprotein S and selenoprotein K through PPAR?-mediated ubiquitination is required for adipocyte differentiation, Cell Death & Differentiation, vol.26, issue.6, pp.1007-1023, 2019. ,
The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration, Biological Trace Element Research, vol.188, issue.1, pp.189-195, 2019. ,
Hypoxia and Reactive Oxygen Species as Modulators of Endoplasmic Reticulum and Golgi Homeostasis, Antioxidants & Redox Signaling, vol.30, issue.1, pp.113-137, 2019. ,
Selenocysteine-Specific Mass Spectrometry Reveals Tissue-Distinct Selenoproteomes and Candidate Selenoproteins, Cell Chemical Biology, vol.25, issue.11, pp.1380-1388, 2018. ,
Selenium and GPX4, a vital symbiosis, Free Radical Biology and Medicine, vol.127, pp.153-159, 2018. ,
Selenoprotein T is a key player in ER proteostasis, endocrine homeostasis and neuroprotection, Free Radical Biology and Medicine, vol.127, pp.145-152, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02427048
, Selenium, Selenoproteins, and Immunity, vol.10, 1203.
Oral supplements of inulin during gestation offsets rotenone-induced oxidative impairments and neurotoxicity in maternal and prenatal rat brain, Biomedicine & Pharmacotherapy, vol.104, pp.751-762, 2018. ,
A selenoprotein T-derived peptide protects the heart against ischaemia/reperfusion injury through inhibition of apoptosis and oxidative stress, Acta Physiologica, vol.223, issue.4, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01939294
A therapeutic role for selenoprotein T in reducing ischaemia/reperfusion injury in the heart?, Acta Physiologica, vol.223, issue.4, 2018. ,
Tyrosine hydroxylase as a sentinel for central and peripheral tissue responses in Parkinson's progression: Evidence from clinical studies and neurotoxin models, Progress in Neurobiology, vol.165, pp.1-25, 2018. ,
Selenoprotein N Was Required for the Regulation of Selenium on the Uterine Smooth Muscle Contraction in Mice, Biological Trace Element Research, vol.183, issue.1, pp.138-146, 2018. ,
Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins, Antioxidants, vol.7, issue.5, 2018. ,
Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis, Cell Calcium, vol.70, pp.76-86, 2018. ,
N-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing, Journal of Cell Biology, vol.217, issue.2, pp.585-599, 2018. ,
, Xin Gen Lei. Selenium and Diabetes, pp.317-344
Selenium and Neurodevelopment 177-192 ,
Selenoprotein T is a novel OST subunit that regulates UPR signaling and hormone secretion, EMBO reports, vol.18, issue.11, pp.1935-1946, 2017. ,
URL : https://hal.archives-ouvertes.fr/inserm-01614090
,
, Selenoprotein T is required for pathogenic bacteria avoidance in Caenorhabditis elegan s, Free Radical Biology and Medicine, vol.108, pp.174-182
, Structure Characterization, and Evaluation in Microglia Cultures of Neuromelanin Analogues Suitable for Modeling Parkinson's Disease, vol.8, pp.501-512, 2017.
Identification of three selenoprotein T paralogs in goldfish (Carassius auratus) and expression analysis in response to environmental stressors, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, vol.203, pp.65-75, 2017. ,
Selenoprotein T: From Discovery to Functional Studies Using Conditional Knockout Mice 275-286 ,
Selenoproteins in Nervous System Development, Function and Degeneration 427-439 ,