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New septanoside and 20-hydroxyecdysone septanoside derivative from Atriplex portulacoides roots with preliminary biological activities

Aymen Ben Nejma 1 Asma Nguir 1 Hichem Ben Jannet 1 M’hamed Ali Hamza 1 Adam Daïch 2, 3 Mohamed Othman 2 Ata Martin Lawson 2, *
* Corresponding author
1 UM - Université de Monastir - University of Monastir
2 URCOM - Unité de Recherche en Chimie Organique et Macromoléculaire
3 INC3M - Institut Normand de Chimie Moléculaire Médicinale et Macromoléculaire
Abstract : The phytochemical investigation of a Tunisian plant Atriplex portulacoides (Chenopodiaceae) led to the isolation of two new compounds designated as portulasoid (2) and septanoecdysone (3) along with the known 20-hydroxyecdysone (20HE) (1). Their chemical structures were elucidated on the basis of extensive spectroscopic methods including ES-HRMS, 1D and 2D-NMR. The isolated compounds were finally tested for their antioxidant activity by using DPPH, ABTS+, Fe3+ and catalase assays and also for their antibacterial and anticholinesterase activities. © 2015 Elsevier Ltd.
Keywords : Septanoecdysone Portulasoid 20-Hydroxyecdysone Atriplex portulacoides Biological activities Chenopodiaceae NMR
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Journal articles
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https://hal-normandie-univ.archives-ouvertes.fr/hal-02413288
Contributor : Vincent Loisel <>
Submitted on : Monday, December 16, 2019 - 10:43:53 AM
Last modification on : Tuesday, October 20, 2020 - 6:48:06 PM

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Aymen Ben Nejma, Asma Nguir, Hichem Ben Jannet, M’hamed Ali Hamza, Adam Daïch, et al.. New septanoside and 20-hydroxyecdysone septanoside derivative from Atriplex portulacoides roots with preliminary biological activities. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2015, 25 (8), pp.1665-1670. ⟨10.1016/j.bmcl.2015.03.028⟩. ⟨hal-02413288⟩

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