Skip to Main content Skip to Navigation
Journal articles

Altered intrinsic connectivity of the auditory cortex in congenital amusia

Abstract : Congenital amusia, a neurodevelopmental disorder of music perception and production, has been associated with abnormal anatomical and functional connectivity in a right frontotemporal pathway. To investigate whether spontaneous connectivity in brain networks involving the auditory cortex is altered in the amusic brain, we ran a seed-based connectivity analysis, contrasting at-rest functional MRI data of amusic and matched control participants. Our results reveal reduced frontotemporal connectivity in amusia during resting state, as well as an overconnectivity between the auditory cortex and the default mode network (DMN). The findings suggest that the auditory cortex is intrinsically more engaged toward internal processes and less available to external stimuli in amusics compared with controls. Beyond amusia, our findings provide new evidence for the link between cognitive deficits in pathology and abnormalities in the connectivity between sensory areas and the DMN at rest.
Document type :
Journal articles
Complete list of metadatas

https://hal-normandie-univ.archives-ouvertes.fr/hal-02386211
Contributor : Mathilde Groussard <>
Submitted on : Friday, November 29, 2019 - 11:21:08 AM
Last modification on : Saturday, October 3, 2020 - 3:26:48 AM

Links full text

Identifiers

Citation

Yohana Lévêque, Baptiste Fauvel, Mathilde Groussard, Anne Caclin, Philippe Albouy, et al.. Altered intrinsic connectivity of the auditory cortex in congenital amusia. Journal of Neurophysiology, American Physiological Society, 2016, 116 (1), pp.88-97. ⟨10.1152/jn.00663.2015⟩. ⟨hal-02386211⟩

Share

Metrics

Record views

84