An approach to the manzamine alkaloids modelled on a biogenetic theory

Jack Baldwin (1) , Laurent Bischoff (2) , Tim D.W. Claridge (1) , Florian Heupel (1) , David Spring (1) , Roger Whitehead (1)

1 University of Oxford
2 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse

Improved conditions for the preparation of 17 are reported together with the synthesis of an advanced intermediate 38 en route to keramaphidin B, a plausible biogenetic precursor to the manzamines. Improved conditions for the preparation of 17 are reported together with the synthesis of an advanced intermediate 38 en route to keramaphidin B, a plausible biogenetic precursor to the manzamines.

Domains: Chemical Sciences; Chemical Sciences; Organic chemistry; Chemical Sciences; Medicinal Chemistry; Chemical Sciences; Radiochemistry; Chemical Sciences; Material chemistry; Chemical Sciences; Inorganic chemistry; Chemical Sciences; Catalysis

Jack Baldwin, Laurent Bischoff, Tim D.W. Claridge, Florian Heupel, David Spring, et al.. An approach to the manzamine alkaloids modelled on a biogenetic theory. Tetrahedron, 1997, 53 (6), pp.2271-2290. ⟨10.1016/S0040-4020(96)01129-5⟩. ⟨hal-02385505⟩