Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines

Samuel Couve-Bonnaire; Jean-François Carpentier; Yves Castanet; Andre Mortreux

doi:10.1016/S0040-4039(99)00596-1

Journal articles

Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines

Samuel Couve-Bonnaire ¹ Jean-François Carpentier ¹ Yves Castanet ¹ Andre Mortreux ¹

1 UCCS - Unité de Catalyse et de Chimie du Solide - UMR 8181

Abstract : 4-Iodopyridiens react with CO and HNEt2 or in the presence of a catalytic amount of PdCl2(PPh3)2 to give the corresponding α-keto amides and esters in fair to high yields. 4-iodopyridines are transformed into the corresponding α-keto amides and esters in moderate to high yields.

Document type :

Journal articles

Domain :

Chemical Sciences / Catalysis

Chemical Sciences / Coordination chemistry

Chemical Sciences / Inorganic chemistry

Chemical Sciences / Organic chemistry

Chemical Sciences / Theoretical and/or physical chemistry

Chemical Sciences

Life Sciences [q-bio] / Biochemistry, Molecular Biology

Life Sciences [q-bio] / Cancer

Life Sciences [q-bio]

Complete list of metadatas

https://hal-normandie-univ.archives-ouvertes.fr/hal-02384504
Contributor : Samuel Couve-Bonnaire <>
Submitted on : Thursday, November 28, 2019 - 1:58:22 PM
Last modification on : Tuesday, November 24, 2020 - 2:18:20 PM

Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines

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Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines

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