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Palladium-catalyzed carbonylative cross-coupling reactions of pyridine halides and aryl boronic acids: a convenient access to α-pyridyl ketones

Abstract : The proper choice of solvent, catalyst precursor and CO pressure enables the easy and selective transformation of mono- and dihalopyridines into phenyl pyridyl ketones in 81–95% yields. The proper choice of solvent, catalyst precursor and CO pressure enables the facile and selective transformation of mono- and dihalopyridines into phenyl pyridyl ketones.
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https://hal-normandie-univ.archives-ouvertes.fr/hal-02384503
Contributor : Samuel Couve-Bonnaire <>
Submitted on : Thursday, November 28, 2019 - 1:57:28 PM
Last modification on : Friday, October 16, 2020 - 11:22:06 AM

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Samuel Couve-Bonnaire, Jean-François Carpentier, Andre Mortreux, Yves Castanet. Palladium-catalyzed carbonylative cross-coupling reactions of pyridine halides and aryl boronic acids: a convenient access to α-pyridyl ketones. Tetrahedron Letters, Elsevier, 2001, 42 (22), pp.3689-3691. ⟨10.1016/S0040-4039(01)00544-5⟩. ⟨hal-02384503⟩

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