Synthesis of 6-Substituted Pyrido[2,3- b ]indoles by Electrophilic Substitution - Archive ouverte HAL Access content directly
Journal Articles SYNLETT Year : 2007

Synthesis of 6-Substituted Pyrido[2,3- b ]indoles by Electrophilic Substitution

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Abstract

Regioselective electrophilic aromatic substitutions, acylation, bromination, and formylation, of unprotected pyrido[2,3-b]indole (α-carbolines) at the C-6 position are described. Alter­native conditions for the nitration were investigated, which led to the ­unexpected appearance of the minor C-8 isomer.
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hal-02380611 , version 1 (26-11-2019)

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Cédric Schneider, David Gueyrard, Florence Popowycz, Benoît Joseph, Peter Goekjian. Synthesis of 6-Substituted Pyrido[2,3- b ]indoles by Electrophilic Substitution. SYNLETT, 2007, 2007 (14), pp.2237-2241. ⟨10.1055/s-2007-985566⟩. ⟨hal-02380611⟩
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