 |
Journal articles
Directed ortho -Metalation–Cross-Coupling Strategies. One-Pot Suzuki Reaction to Biaryl and Heterobiaryl Sulfonamides
Abstract : A general synthesis of stable ortho-boropinacolato aryl and heteroaryl sulfonamides by directed ortho-metalation (DoM) and either MeOBPin or i-PrOBpin electrophile quench, 3 → 4, is described. A one-pot metalation–Suzuki cross-coupling procedure for the synthesis of biaryls and heterobiaryls, 3 → 5, and a complementary DoM–Ir-catalyzed boronation sequence (Scheme 6) are delineated.
https://hal-normandie-univ.archives-ouvertes.fr/hal-02380533
Contributor : Cédric Schneider Connect in order to contact the contributor
Submitted on : Tuesday, November 26, 2019 - 12:00:47 PM
Last modification on : Tuesday, October 19, 2021 - 11:34:48 PM
Contributor : Cédric Schneider Connect in order to contact the contributor
Submitted on : Tuesday, November 26, 2019 - 12:00:47 PM
Last modification on : Tuesday, October 19, 2021 - 11:34:48 PM
