Skip to Main content Skip to Navigation
Poster communications

Expanding the gene regulatory network in response to osmotic stress in the halophilic Chromohalobacter salexigens

Montserrat Argandoña 1 Rosa García-Valero 1 Ali Tahrioui 2, 1 Joaquín José Nieto 1 Carmen Vargas 1
1 Department of Microbiology and Parasitology, University of Sevilla
2 LMSM - Laboratoire de Microbiologie Signaux et Microenvironnement
Abstract : Background: Chromohalobacter salexigens is a broad-growing halophilic bacterium considered as a biological model to study osmoadaptation and a cell factory for the production of ectoines, biostabilizing compatible solutes which have many biotechnological applications. To design new metabolic engineering strategies to obtain improved ectoines production strains of C. salexigens, a preliminary transcriptional regulatory network (TRN) core was reconstructed by using an integrative approach that combined RNAseq data from wild type and different in silico analyses. This core constituted by 598 genes and 1192 regulatory interactions was used to analyse molecular regulation events involved in metabolic osmotic stress response and ectoines metabolism.
Document type :
Poster communications
Complete list of metadatas
https://hal-normandie-univ.archives-ouvertes.fr/hal-02378289
Contributor : Ali Tahrioui <>
Submitted on : Thursday, November 28, 2019 - 4:44:07 PM
Last modification on : Sunday, December 1, 2019 - 1:23:17 AM

Identifiers

  • HAL Id : hal-02378289, version 1

Collections

COMUE-NORMANDIE | UNIROUEN | LMSM

Citation

Montserrat Argandoña, Rosa García-Valero, Ali Tahrioui, Joaquín José Nieto, Carmen Vargas. Expanding the gene regulatory network in response to osmotic stress in the halophilic Chromohalobacter salexigens. 7th Congress of European Microbiologists-FEMS2017, Jul 2017, Valence, Spain. ⟨hal-02378289⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

15