Improvement of a Biomimetic Porphyrin Catalytic System by Addition of Acids
Résumé
The conditions of the use of the manganese/porphyrin/imidazole system needed to be improved in order to
obtain larger amounts of models of metabolites. An increase of the oxidation yields and a better preservation of
this catalytic system have been obtained on the examples of various alkanes, by an acid addition in the reaction
mixture. Three manganoporphyrins were checked for evaluation of the reaction. These results were extended to
molecules of therapeutical interest such as ibuprofen and phenylbutazone.