Skip to Main content Skip to Navigation
Journal articles

Postoperative Morbidity After Iterative Ileocolonic Resection for Crohn’s Disease: Should we be Worried? A Prospective Multicentric Cohort Study of the GETAID Chirurgie

Solafah Abdalla 1, 2 Antoine Brouquet 3 Léon Maggiori 4 Philippe Zerbib 5 Quentin Denost 6 Adeline Germain 7 Eddy Cotte 8 Laura Beyer-Berjot 9 Nicolas Munoz-Bongrand 10 Véronique Desfourneaux 11 Amine Rahili 12 Jean-Pierre Duffas 13 Karine Pautrat 14 Christine Denet 15 Valérie Bridoux 16, 17, 18, 19 Guillaume Meurette 20 Jean-Luc Faucheron 21 Jérôme Loriau 22 Françoise Guillon 23 Eric Vicaut 15 Stéphane Benoist 3 Yves Panis 24 Jérémie Lefèvre 2, 1 
Abstract : BACKGROUND AND AIMS: To compare perioperative characteristics and outcomes between primary ileocolonic resection [PICR] and iterative ileocolic resection [IICR] for Crohn's disease [CD]. METHODS: From 2013 to 2015, 567 patients undergoing ileocolonic resection were prospectively included in 19 centres of the GETAID chirurgie group. Perioperative characteristics and postoperative results of both groups [431 PICR, 136 IICR] were compared. Uni- and multivariate analyses of the risk factors of overall 30-day postoperative morbidity was carried out in the IICR group. RESULTS: IICR patients were less likely to be malnourished [27.2% vs 39.9%, p = 0.007], and had more stricturing forms [69.1% vs 54.3%, p = 0.002] and less perforating disease [19.9% vs 39.2%, p < 0.001]. Laparoscopy was less commonly used in IICR [45.6% vs 84.5%, p < 0.01] and was associated with increased conversion rates [27.4% vs 14.6%, p = 0.012]. Overall postoperative morbidity was 36.8% in the IICR group and 26.7% in the PICR group [p = 0.024]. There was no significant difference between IICR and PICR regarding septic intra-abdominal complications, anastomotic leakage [8.8% vs 8.4%] or temporary stoma requirement. IICR patients were more likely to present with non-infectious complications and ileus [11.8% vs 3.7%, p < 0.001]. Uni- and multivariate analyses did not identify specific risk factors of overall postoperative morbidity in the IICR group. CONCLUSIONS: Surgery for recurrent CD is associated with a slight increase of non-infectious morbidity [postoperative ileus] that mainly reflects the technical difficulties of these procedures. However, IICR remains a safe therapeutic option in patients with recurrent CD because severe morbidity including anastomotic complications is similar to patients undergoing primary resection.
Complete list of metadata

Cited literature [27 references]  Display  Hide  Download
Contributor : sabine douville Connect in order to contact the contributor
Submitted on : Wednesday, January 22, 2020 - 11:53:14 AM
Last modification on : Thursday, August 4, 2022 - 5:25:43 PM
Long-term archiving on: : Thursday, April 23, 2020 - 12:45:16 PM


Abdalla et al. - 2019 - Postop...
Files produced by the author(s)



Solafah Abdalla, Antoine Brouquet, Léon Maggiori, Philippe Zerbib, Quentin Denost, et al.. Postoperative Morbidity After Iterative Ileocolonic Resection for Crohn’s Disease: Should we be Worried? A Prospective Multicentric Cohort Study of the GETAID Chirurgie. Journal of Crohn's and Colitis, Elsevier - Oxford University Press, 2019, 13 (12), pp.1510-1517. ⟨10.1093/ecco-jcc/jjz091⟩. ⟨hal-02362759⟩



Record views


Files downloads