Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis

Beng Hooi Phang , Rashidah Othman , Gaëlle Bougeard (1) , Ren Hui Chia , Thierry Frébourg (1) , Choong Leong Tang , Peh Yean Cheah , Kanaga Sabapathy

1 GMFC - Génétique du cancer et des maladies neuropsychiatriques

Domains: Human genetics

Beng Hooi Phang, Rashidah Othman, Gaëlle Bougeard, Ren Hui Chia, Thierry Frébourg, et al.. Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (46), pp.E6349-E6358. ⟨10.1073/pnas.1510043112⟩. ⟨hal-02356393⟩