 |
Journal articles
Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors in Amphibians
Laurent Yon
1, 2
David Alexandre
3
Maité Montéro
2
Nicolas Chartrel
2
Lydie Jeandel
3
Mauro Vallarino
4
J. Michael Conlon
5
Sakae Kikuyama
6
Alain Fournier
7
Francisco Gracia-Navarro
8
Eric Roubos
9
Billy Chow
10
Akira Arimura
Youssef Anouar
3
Hubert Vaudry
1, 2
Laurent Yon 1, 2
Author IdHAL : laurent-yon ResearcherId : http://www.researcherid.com/rid/E-1981-2016 IdRef : https://www.idref.fr/114724849 ORCID : https://orcid.org/0000-0002-5420-5779
David Alexandre 3
Author
Maité Montéro 2
Author IdHAL : maite-montero-hadjadje ORCID : https://orcid.org/0000-0001-8859-893X
Nicolas Chartrel 2
Author
Lydie Jeandel 3
Author
Mauro Vallarino 4
Author
J. Michael Michael Conlon 5
Author
Sakae Kikuyama 6
Author
Alain Fournier 7
Author
Francisco Gracia-Navarro 8
Author
Eric Roubos 9
Author
Billy K C Chow 10
Author
1
Neuroendocrinologie cellulaire et moléculaire (Universite de Rouen 76821 MONT-SAINT-AIGNAN CEDEX - France)
- UNIROUEN - Université de Rouen Normandie : U413 (1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex - France)
- NU - Normandie Université (Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U413 (101, rue de Tolbiac, 75013 Paris - France)
2
DC2N - Différenciation et communication neuronale et neuroendocrine (Place Emile Blondel Faculté des Sciences et Techniques 76821 Mont-Saint-Aignan Cedex - France)
- UNIROUEN - Université de Rouen Normandie : U1239 (1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex - France)
- NU - Normandie Université (Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U1239 (101, rue de Tolbiac, 75013 Paris - France)
3
DC2N - Différenciation et communication neuronale et neuroendocrine (Place Emile Blondel Faculté des Sciences et Techniques 76821 Mont-Saint-Aignan Cedex - France)
- UNIROUEN - Université de Rouen Normandie : U982 (1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex - France)
- NU - Normandie Université (Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U982 (101, rue de Tolbiac, 75013 Paris - France)
4
UNIGE - Université de Genève (24 rue du Général-Dufour CH - 1211 Genève 4 - Switzerland)
5
University of Ulster (University of Ulster Cromore Road Coleraine Co. Londonderry BT52 1SA - Ireland)
6
Waseda University (1-104 Totsukamachi, Shinjuku-ku, Tokyo, 169-8050, JAPAN - Japan)
7
INRS-IAF - Institut Armand Frappier (531 boul. des Prairies Laval (Québec) H7V 1B7 - Canada)
- INRS - Institut National de la Recherche Scientifique [Québec] (490 rue de la Couronne, Québec, QC G1K 9A9 - Canada)
- RIIP - Réseau International des Instituts Pasteur (25, rue du Dr Roux 75724 Paris Cedex 15 - France)
8
University of Córdoba [Córdoba] (Avd. Medina Azahara, 5 14071 Córdoba - Spain)
9
Radboud university [Nijmegen] (Comeniuslaan 4, 6525 HP Nijmegen - Netherlands)
10
HKU - The University of Hong Kong (Pokfulam, Hong Kong - Hong Kong SAR China)
Abstract : Pituitary adenylate cyclase-activating polypeptide (PACAP), a novel peptide of the secretin/glucagon/vasoactive intestinal polypeptide superfamily, has been initially characterized in mammals in 1989 and, only 2 years later, its counterpart has been isolated in amphibians. A number of studies conducted in the frog Rana ridibunda have demonstrated that PACAP is widely distributed in the central nervous system (particularly in the hypothalamus and the median eminence) and in peripheral organs including the adrenal gland. The cDNAs encoding the PACAP precursor and 3 types of PACAP receptors have been cloned in amphibians and their distribution has been determined by in situ hybridization histochemistry. Ontogenetic studies have revealed that PACAP is expresssed early in the brain of tadpoles, soon after hatching. In the frog Rana ridibunda, PACAP exerts a large array of biological effects in the brain, pituitary, adrenal gland, and ovary, suggesting that, in amphibians as in mammals, PACAP may act as neurotrophic factor, a neurotransmitter and a neurohormone. Microsc. Res. Tech. 54:137-157, 2001.
Document type :
Journal articles
Domain :
Complete list of metadatas
https://hal-normandie-univ.archives-ouvertes.fr/hal-02334700
Contributor : Laurent Yon <>
Submitted on : Tuesday, October 29, 2019 - 4:36:07 PM
Last modification on : Tuesday, April 7, 2020 - 3:36:04 PM
Contributor : Laurent Yon <>
Submitted on : Tuesday, October 29, 2019 - 4:36:07 PM
Last modification on : Tuesday, April 7, 2020 - 3:36:04 PM
Links full text
Identifiers
- HAL Id : hal-02334700, version 1
- DOI : 10.1002/jemt.1129
Collections
COMUE-NORMANDIE | RIIP | INRS-IAF | UNIROUEN | DC2N
Citation
Laurent Yon, David Alexandre, Maité Montéro, Nicolas Chartrel, Lydie Jeandel, et al.. Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors in Amphibians. Microscopy Research and Technique, Wiley, 2001, 54 (3), pp.137-157. ⟨10.1002/jemt.1129⟩. ⟨hal-02334700⟩
Metrics
Record views
