Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein

Sébastien Feuillette (1) , Laetitia Miguel (1) , Thierry Frebourg (2) , Dominique Campion (2) , Magalie Lecourtois (1)

1 GPMCND - Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques
2 Génétique médicale et fonctionnelle du cancer et des maladies neuropsychiatriques

Domains: Life Sciences [q-bio]; Neurons and Cognition [q-bio.NC]

Sébastien Feuillette, Laetitia Miguel, Thierry Frebourg, Dominique Campion, Magalie Lecourtois. Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein. Journal of Neurochemistry, 2010, 113 (4), pp.895-903. ⟨10.1111/j.1471-4159.2010.06663.x⟩. ⟨hal-02332582⟩