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Journal articles
[Depression of the efferent activity of the cerebellar nuclei following destruction of the inferior olive].
Abstract : The spontaneous discharge frequency of the fastigial and interpositus nuclei was evaluated in three experimental conditions in Rat: (a) in the "intact" animal; (b) in animals with total and selective destruction of the inferior olive, depriving the Purkinje cells of their afferent climbing fiber; (c) in animals having inferior olive destruction and cryocoagulation of the cerebellar cortex, destroying Purkinje cells innervating the neurones of the fastigial and interpositus nuclei. Unit activity was high in group (a) (32.9 +/- 22.9/s); it was markedly reduced in group (b) (1.1 +/- 1.3/s); it was higher in group (c) than in group (a) (43.7 +/- 25.5/s). Suppression of the inferior olive thus increases the Purkinje cell inhibitory action upon neurones of the cerebellar nuclei.
https://hal-normandie-univ.archives-ouvertes.fr/hal-02325810
Contributor : Jean-Marie Billard <>
Submitted on : Tuesday, October 22, 2019 - 12:42:33 PM
Last modification on : Thursday, April 30, 2020 - 1:37:42 AM
Contributor : Jean-Marie Billard <>
Submitted on : Tuesday, October 22, 2019 - 12:42:33 PM
Last modification on : Thursday, April 30, 2020 - 1:37:42 AM
