Invasive Geotrichum clavatum Fungal Infection in an Acute Myeloid Leukaemia Patient: A Case Report and Review

Abstract : Invasive Geotrichum clavatum fungal infections are extremely rare and unusual, occurring nearly exclusively in patients experiencing prolonged neutropenia during the treatment for acute myeloid leukaemia. Several groups of cases of fatal G. clavatum infection were reported in France between 2011 and 2012, but the ecological niche has not yet been identified. We report a case of a 32-year-old patient with acute myeloid leukaemia who developed G. clavatum sepsis with primary peritonitis, hepatic nodular lesions, and multivisceral failure during apla-sia after induction followed by salvage chemotherapy. He was treated with voriconazole and is still alive 1 year after with controlled disease. We then discuss the epidemiological, clinical, and therapeutic features of these serious fungal infections compared to the published data.
Liste complète des métadonnées

Littérature citée [33 références]  Voir  Masquer  Télécharger

https://hal-normandie-univ.archives-ouvertes.fr/hal-02317977
Contributeur : Venceslas Villier <>
Soumis le : jeudi 17 octobre 2019 - 09:50:54
Dernière modification le : samedi 19 octobre 2019 - 01:13:33

Identifiants

Collections

Citation

Vincent Camus, Marie-Laure Thibault, Marion David, Gilles Gargala, Patricia Compagnon, et al.. Invasive Geotrichum clavatum Fungal Infection in an Acute Myeloid Leukaemia Patient: A Case Report and Review. Mycopathologia, Springer Verlag, 2014, 177 (5-6), pp.319-324. ⟨10.1007/s11046-014-9746-4⟩. ⟨hal-02317977⟩

Partager

Métriques

Consultations de la notice

5