Skip to Main content Skip to Navigation
Journal articles

Effects of aging on structure and stability of TiO2 nanoparticle-containing oil-in-water emulsions

Abstract : Formulations incorporating different cosmetic grade TiO 2 nanoparticles were developed according to a self-produced protocol on the basis of typical sunscreen cream oil-in-water emulsions. Role of nanopar-ticles and, more specifically, the impact of two different lipophilic surface treatments on microstructure and stability of the formulations were assessed. Aging of formulations was performed under classical conditions at room temperature or under accelerated conditions at 50 • C, with or without TiO 2 , and was characterized by several tools such as rheology, microscopy, and particle size measurements. Changes in emulsion stability and aggregation state of nanoparticles were followed over time. Destabilization phenomena were identified: under accelerated aging, the formulation without nanoparticles underwent a coalescence occurrence whereas the formulation incorporating nanoparticles was subjected to aggregation of the colloidal particles. Besides, TiO 2 nanoparticles strongly affected the particle-droplets interactions and thus modified the emulsion microstructure with a coating-dependent effect: destabilization mechanisms occur more rapidly with alumina (and) triethoxycaprylylsilane (coating 1) TiO 2 nanoparticles as compared to alumina (and) isopropyl titanium triisostearate (and) triethoxycaprylylsi-lane crosspolymer (coating 2) nanoparticles.
Complete list of metadatas

Cited literature [20 references]  Display  Hide  Download

https://hal-normandie-univ.archives-ouvertes.fr/hal-02310811
Contributor : Nicolas Hucher <>
Submitted on : Thursday, October 24, 2019 - 11:52:26 AM
Last modification on : Saturday, June 6, 2020 - 4:13:21 AM
Long-term archiving on: : Saturday, January 25, 2020 - 2:51:07 PM

File

Rossano et al_2014_Internation...
Files produced by the author(s)

Identifiers

Collections

Citation

Manon Rossano, Nicolas Hucher, Celine Picard, Daniel Colletta, Frank Le Foll, et al.. Effects of aging on structure and stability of TiO2 nanoparticle-containing oil-in-water emulsions. International Journal of Pharmaceutics, Elsevier, 2014, 461 (1-2), pp.89-96. ⟨10.1016/j.ijpharm.2013.11.039⟩. ⟨hal-02310811⟩

Share

Metrics

Record views

77

Files downloads

212