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Cancer and RASSF1A/RASSF1C, the two faces of Janus.

Abstract : Although encoded by the same gene, RASSF1A and RASSF1C are two opposites in carcinogenesis; one is a tumor suppressor that is silenced in a plethora of cancers, while the other is an oncogene that remains unaffected. Here, we aim to understand why and to highlight their respective clinical implications.
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Submitted on : Thursday, October 10, 2019 - 9:12:17 AM
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Fatéméh Dubois, Emmanuel Bergot, Guénaëlle Levallet. Cancer and RASSF1A/RASSF1C, the two faces of Janus.. Trends in Cancer, Cell Press, 2019, 5 (11), pp.662-665. ⟨10.1016/j.trecan.2019.10.001⟩. ⟨hal-02310265⟩



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