Incidence and Phenotype at Diagnosis of Very-early-onset Compared with Later-onset Paediatric Inflammatory Bowel Disease: A Population-based Study [1988–2011]

E. Bequet (1) , H. Sarter (2, 3) , Mathurin Fumery (4, 2) , F. Vasseur (5) , L. Armengol-Debeir (6) , B. Pariente (7) , D. Ley (8, 3) , C. Spyckerelle (9) , H. Coevoet (10) , J. Laberenne (11) , L. Peyrin-Biroulet (12) , G. Savoye (13, 14, 15, 6) , D. Turck (8, 3) , C. Gower-Rousseau (5, 2, 3)

1 Hôpital Jeanne de Flandres
2 Registre EPIMAD
3 LIRIC - Lille Inflammation Research International Center - U 995
4 CHU Amiens-Picardie
5 METRICS - Evaluation des technologies de santé et des pratiques médicales - ULR 2694
6 Service d'Hépato-Gastroentérologie [CHU Rouen]
7 Hôpital Claude Huriez [Lille]
8 Hôpital Jeanne de Flandre [Lille]
9 Unité Pédiatrique [Saint-Vincent de Paul Lille]
10 Hôpital privé Arras les Bonnettes
11 Service d'Hépato-Gastroenterologie [Seclin]
12 CHRU Nancy - Centre Hospitalier Régional Universitaire de Nancy
13 ADEN - Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau
14 IRIB - Institute for Research and Innovation in Biomedicine
15 UNIROUEN - Université de Rouen Normandie

Very-early-onset inflammatory bowel disease [VEO-IBD] is a form of IBD that is distinct from that of children with an older onset. We compared changes over time in the incidence and phenotype at diagnosis between two groups according to age at IBD diagnosis: VEO-IBD diagnosed before the age of 6 years, and early-onset IBD [EO-IBD] diagnosed between 6 and 16 years of age.

Mots clés: Inflammatory bowel disease; paediatric; very-early-onset; incidence; clinical presentation

Domaines: Hépatologie et Gastroentérologie

E. Bequet, H. Sarter, Mathurin Fumery, F. Vasseur, L. Armengol-Debeir, et al.. Incidence and Phenotype at Diagnosis of Very-early-onset Compared with Later-onset Paediatric Inflammatory Bowel Disease: A Population-based Study [1988–2011]. Journal of Crohn's and Colitis, 2016, pp.jjw194. ⟨10.1093/ecco-jcc/jjw194⟩. ⟨hal-02301530⟩