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Selective Heart Rate Reduction Improves Metabolic Syndrome–related Left Ventricular Diastolic Dysfunction

Abstract : Enhanced heart rate observed in metabolic syndrome (MS) contributes to the deterioration of left ventricular (LV) function via impaired LV filling and relaxation, increased myocardial O2 consumption, and reduced coronary perfusion. However, whether heart rate reduction (HRR) opposes LV dysfunction observed in MS is unknown.
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https://hal-normandie-univ.archives-ouvertes.fr/hal-02300715
Contributor : Christelle Monteil <>
Submitted on : Sunday, September 29, 2019 - 3:41:25 PM
Last modification on : Monday, July 6, 2020 - 12:34:02 PM

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Nassiba Merabet, Yuehua Fang, Lionel Nicol, Christelle Monteil, Isabelle Remy-Jouet, et al.. Selective Heart Rate Reduction Improves Metabolic Syndrome–related Left Ventricular Diastolic Dysfunction. Journal of Cardiovascular Pharmacology, Lippincott, Williams & Wilkins, 2015, 66 (4), pp.399-408. ⟨10.1097/FJC.0000000000000294⟩. ⟨hal-02300715⟩

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