A specific prediction equation is necessary to estimate peak oxygen uptake in obese patients with metabolic syndrome

Abstract : Purpose The aims were to: (1) compare peak oxygen uptake (V˙O2 peak) predicted from four standard equations to actual V˙O2peak measured from a cardiopulmonary exercise test (CPET) in obese patients with metabolic syndrome (MetS), and (2) develop a new equation to accurately estimate V˙O2 peak in obese women with MetS. Methods Seventy-five obese patients with MetS performed a CPET. Anthropometric data were also collected for each participant. V˙O2 peak was predicted from four prediction equations (from Riddle et al., Hansen et al., Wasserman et al. or Gläser et al.) and then compared with the actual V˙O2 peak measured during the CPET. The accuracy of the predictions was determined with the Bland–Altman method. When accuracy was low, a new prediction equation including anthropometric variables was proposed. Results V˙O2 peak predicted from the equation of Wasserman et al. was not significantly different from actual V˙O2peak in women. Moreover, a significant correlation was found between the predicted and actual values (p < 0.001, r = 0.69). In men, no significant difference was noted between actual V˙O2peak and V˙O2 peak predicted from the prediction equation of Gläser et al., and these two values were also correlated (p = 0.03, r = 0.44). However, the LoA95% was wide, whatever the prediction equation or gender. Regression analysis suggested a new prediction equation derived from age and height for obese women with MetS. Conclusions The methods of Wasserman et al. and Gläser et al. are valid to predict V˙O2 peak in obese women and men with MetS, respectively. However, the accuracy of the predictions was low for both methods. Consequently, a new prediction equation including age and height was developed for obese women with MetS. However, new prediction equation remains to develop in obese men with MetS.
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Contributeur : Sabine Douville <>
Soumis le : lundi 16 septembre 2019 - 16:26:16
Dernière modification le : jeudi 10 octobre 2019 - 11:46:04

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D. Debeaumont, C. Tardif, V. Folope, I. Castres, F. Lemaitre, et al.. A specific prediction equation is necessary to estimate peak oxygen uptake in obese patients with metabolic syndrome. Journal of Endocrinological Investigation, Editrice Kurtis, 2016, 39 (6), pp.635-642. ⟨10.1007/s40618-015-0411-7⟩. ⟨hal-02289399⟩

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