Skip to Main content Skip to Navigation
Journal articles

Copper‐Photocatalyzed Borylation of Organic Halides under Batch and Continuous‐Flow Conditions

Abstract : The copper‐photocatalyzed borylation of aryl, heteroaryl, vinyl and alkyl halides (I and Br) was reported. The reaction proceeded using a new heteroleptic Cu complex under irradiation with blue LEDs, giving the corresponding boronic‐acid esters in good to excellent yields. The reaction was extended to continuous‐flow conditions to allow an easy scale‐up. The mechanism of the reaction was studied and a mechanism based on a reductive quenching (CuI/CuI*/Cu0) was suggested.
Document type :
Journal articles
Complete list of metadatas

https://hal-normandie-univ.archives-ouvertes.fr/hal-02278783
Contributor : Madeleine Roux-Merlin <>
Submitted on : Wednesday, September 4, 2019 - 3:59:18 PM
Last modification on : Thursday, July 2, 2020 - 3:30:04 AM

Identifiers

Citation

Antoine Nitelet, Damien Thevenet, Bruno Schiavi, Christophe Hardouin, Jean Fournier, et al.. Copper‐Photocatalyzed Borylation of Organic Halides under Batch and Continuous‐Flow Conditions. Chemistry - A European Journal, Wiley-VCH Verlag, 2019, 25 (13), pp.3262-3266. ⟨10.1002/chem.201806345⟩. ⟨hal-02278783⟩

Share

Metrics

Record views

50