Usefulness of Flow Cytometry for the Detection of Cutaneous Localization in Malignant Hematologic Disorders

Elsa Maitre (1, 2) , Anne-Laure Le-Page (1) , Francois Comoz (1) , Florence Truquet (1) , Gandhi Damaj (1) , Edouard Cornet (1, 2) , Laurence Verneuil (1) , Véronique Salaün (1) , Xavier Troussard (1, 2)

1 CHU Caen
2 GPMCND - Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques

Histological evaluation of malignant hematologic involvement of the skin can be challenging and needs an extended immunohistochemistry panel. We assessed the ability of flow cytometry (FCM) to detect neoplastic cell subsets in skin biopsies as a useful tool that supplements the histological examination in a complementary way.

Keywords: CD26; Sézary syndrome; biopsy; mycosis Fungoides; skin

Domains: Life Sciences [q-bio]; Human health and pathology

Elsa Maitre, Anne-Laure Le-Page, Francois Comoz, Florence Truquet, Gandhi Damaj, et al.. Usefulness of Flow Cytometry for the Detection of Cutaneous Localization in Malignant Hematologic Disorders. Cytometry. Part B, Clinical Cytometry, 2019, 96 (4), pp.283-293. ⟨10.1002/cyto.b.21784⟩. ⟨hal-02194331⟩