Relationships between Oxidative Stress Response and Virulence in Enterococcus faecalis

Eliette Riboulet (1) , Nicolas Verneuil (1) , Stéphanie La Carbona (1) , Nicolas Sauvageot (1) , Yanick Auffray (1) , Axel Hartke (1) , Jean-Christophe Giard (1)

1 LME - Laboratoire de Microbiologie de l’Environnement

Enterococcus faecalis is a Gram-positive bacterium, member of the lactic acid bacteria group and is also one of the major causative agents of nosocomial infections. Moreover, the oxidative stress is one of the main challenges bacteria have to cope with during their process of infection. This review gives a description of this opportunist pathogen bacterium and an overview of the oxidative stress response and its regulation. We subsequently summarize results that suggest a relationship between this stress response and the virulence in E. faecalis.

Keywords: Enterococcus faecalis; Oxidative stress; Virulence

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Biochemistry, Molecular Biology

Eliette Riboulet, Nicolas Verneuil, Stéphanie La Carbona, Nicolas Sauvageot, Yanick Auffray, et al.. Relationships between Oxidative Stress Response and Virulence in Enterococcus faecalis. Journal of Molecular Microbiology and Biotechnology, 2007, 13 (1-3), pp.140-146. ⟨10.1159/000103605⟩. ⟨hal-02181003⟩