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Journal articles
Well-Defined Phosphine-Free Iron-Catalyzed N -Ethylation and N -Methylation of Amines with Ethanol and Methanol
Abstract : An iron(0) complex bearing a cyclopentadienone ligand catalyzed N-methylation and N-ethylation of aryl and aliphatic amines with methanol or ethanol in mild and basic conditions through a hydrogen autotransfer borrowing process is reported. A broad range of aromatic and aliphatic amines underwent mono- or dimethylation in high yields. DFT calculations suggest molecular hydrogen acts not only as a reducing agent but also as an additive to displace thermodynamic equilibria.
https://hal-normandie-univ.archives-ouvertes.fr/hal-02159935
Contributor : Jean-Luc Renaud <>
Submitted on : Wednesday, June 19, 2019 - 10:44:06 AM
Last modification on : Thursday, July 2, 2020 - 3:21:26 AM
Contributor : Jean-Luc Renaud <>
Submitted on : Wednesday, June 19, 2019 - 10:44:06 AM
Last modification on : Thursday, July 2, 2020 - 3:21:26 AM
