Recent Progress Toward the Synthesis of Trifluoromethyl- and Difluoromethyl-Substituted Cyclopropanes

Maxence Bos (1) , Thomas Poisson (1) , Xavier Pannecoucke (1) , André B. Charette , Philippe Jubault (1)

1 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse

This Minireview describes recent advances toward the synthesis of trifluoromethyl‐ and difluoromethyl‐substituted cyclopropanes. Synthetic methodologies using [2+1] cycloaddition, ring‐contraction, and ring‐closure cyclopropanations since 2010 are reported.

Domains: Chemical Sciences

Maxence Bos, Thomas Poisson, Xavier Pannecoucke, André B. Charette, Philippe Jubault. Recent Progress Toward the Synthesis of Trifluoromethyl- and Difluoromethyl-Substituted Cyclopropanes. Chemistry - A European Journal, 2017, 23 (21), pp.4950-4961. ⟨10.1002/chem.201604564⟩. ⟨hal-02046262⟩