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Journal articles
An Electrophilic Reagent for the Direct Introduction of the SCF2PO(OEt)2Group to Molecules
Abstract : An unprecedented electrophilic difluoromethylthiolating reagent (MesNHSCF2PO(OEt)2) was designed. Under mild and metal‐free conditions, this new reagent reacted with various nucleophiles, thus offering an efficient and operationally simple tool for the construction of C−SCF2PO(OR)2, N−SCF2PO(OR)2, and S−SCF2PO(OR)2 bonds. Finally, thanks to this new methodology, the synthesis of the non‐stereoidal anti‐inflammatory diflumidone was achieved.
https://hal-normandie-univ.archives-ouvertes.fr/hal-02046245
Contributor : Madeleine Roux-Merlin <>
Submitted on : Friday, February 22, 2019 - 3:37:30 PM
Last modification on : Tuesday, November 3, 2020 - 9:50:05 AM
Contributor : Madeleine Roux-Merlin <>
Submitted on : Friday, February 22, 2019 - 3:37:30 PM
Last modification on : Tuesday, November 3, 2020 - 9:50:05 AM
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