Skip to Main content Skip to Navigation
Journal articles

Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate

Abstract : An efficient Pd-catalyzed carbonylation protocol is described for the coupling of a large panel of aryl, heteroaryl, benzyl, vinyl and allyl halides 2 with the unusual N-hydroxysuccinimidyl (NHS) formate 1 as a CO surrogate to afford the corresponding valuable NHS esters 3. High conversion to the coupling products was achieved with up to 98% yield by means of Pd(OAc)2/Xantphos catalyst system.
Document type :
Journal articles
Complete list of metadatas

https://hal-normandie-univ.archives-ouvertes.fr/hal-02046139
Contributor : Madeleine Roux-Merlin <>
Submitted on : Friday, February 22, 2019 - 3:31:52 PM
Last modification on : Thursday, July 2, 2020 - 3:28:33 AM

Identifiers

Citation

Anaïs Barré, Mihaela-Liliana Tîntas, Florent Alix, Vincent Gembus, Cyril Papamicaël, et al.. Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate. Journal of Organic Chemistry, American Chemical Society, 2015, 80 (13), pp.6537-6544. ⟨10.1021/acs.joc.5b01119⟩. ⟨hal-02046139⟩

Share

Metrics

Record views

40