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Journal articles
Straightforward Entry toward Highly Substituted 2,3-Dihydrobenz[b]oxepines by Ring Expansion of Benzopyryliums with Donor-Acceptor Diazo Compounds
Abstract : Ylide-type reactivity of diazo compounds is exploited in a new way to prepare benzo[b]oxepines thanks to the formation of three chemical bonds and two contiguous and highly substituted stereocenters in a single pot. This cationic reaction cascade first involves addition of a donor–acceptor-substituted diazo compound to a benzopyrylium. Selective 1,2 migration of the endocyclic C–C bond then results in a ring-expansion and generates a second oxocarbenium that is trapped by a nucleophile added sequentially.
https://hal-normandie-univ.archives-ouvertes.fr/hal-02024492
Contributor : Madeleine Roux-Merlin <>
Submitted on : Tuesday, February 19, 2019 - 11:09:30 AM
Last modification on : Wednesday, January 6, 2021 - 6:32:02 PM
Contributor : Madeleine Roux-Merlin <>
Submitted on : Tuesday, February 19, 2019 - 11:09:30 AM
Last modification on : Wednesday, January 6, 2021 - 6:32:02 PM
