Antimicrobial peptides of multicellular organisms, Nature, vol.415, pp.389-95, 2002. ,
Antimicrobial peptides for therapeutic applications: a review, Molecules, vol.17, pp.12276-86, 2012. ,
Why and how are peptide-lipid interactions utilized for selfdefense? Magainins and tachyplesins as archetypes, Biochim Biophys Acta, vol.1462, pp.1-10, 1999. ,
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell nonselective membrane-lytic peptides, Biochim Biophys Acta, vol.1462, pp.55-70, 1999. ,
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?, Nat Rev Microbiol, vol.3, pp.238-50, 2005. ,
Antimicrobial peptides in animals and their role in host defences, Int J Antimicrob Agents, vol.22, pp.465-78, 2003. ,
Peptide antimicrobial agents, Clin Microbiol Rev, vol.19, pp.491-511, 2006. ,
Immune modulation by multifaceted cationic host defense (antimicrobial) peptides, Nat Chem Biol, vol.9, pp.761-769, 2013. ,
Host defense peptides: front-line immunomodulators, Trends Immunol, vol.35, pp.443-50, 2014. ,
Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections, Emerg Health Threats J, vol.2, p.1, 2009. ,
Human antimicrobial peptides: defensins, cathelicidins and histatins, Biotechnol Lett, vol.27, pp.1337-1384, 2005. ,
Participation of mammalian defensins and cathelicidins in anti-microbial immunity: receptors and activities of human defensins and cathelicidin (LL-37), J Leukoc Biol, vol.69, pp.691-698, 2001. ,
Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs, J Immunol, vol.183, pp.5788-98, 2009. ,
The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes, J Immunol, vol.172, pp.3758-65, 2004. ,
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release, J Immunol, vol.172, pp.4987-94, 2004. ,
Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways, J Immunol, vol.179, pp.7684-91, 2007. ,
The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils, Eur J Immunol, vol.40, pp.1118-1144, 2010. ,
The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses, J Immunol, vol.169, pp.3883-91, 2002. ,
P2X7 receptor regulates internalization of antimicrobial peptide LL-37 by human macrophages that promotes intracellular pathogen clearance, J Immunol, vol.195, pp.1191-201, 2015. ,
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system, J Leukoc Biol, vol.80, pp.509-529, 2006. ,
The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium, Am J Respir Cell Mol Biol, vol.43, pp.692-702, 2010. ,
In vitro and in vivo wound healing-promoting activities of human cathelicidin LL-37, J Invest Dermatol, vol.128, pp.223-259, 2008. ,
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18, J Clin Invest, vol.111, pp.1665-72, 2003. ,
Cathelicidin LL-37 induces angiogenesis via PGE2-EP3 signaling in endothelial cells, in vivo inhibition by aspirin, Arterioscler Thromb Vasc Biol, vol.33, pp.1965-72, 2013. ,
Non-disulfide-bridged peptides from Tityus serrulatus venom: evidence for proline-free ACE-inhibitors, Peptides, vol.82, pp.44-51, 2016. ,
The honeybee antimicrobial peptide apidaecin differentially immunomodulates human macrophages, monocytes and dendritic cells, J Innate Immun, vol.3, pp.614-636, 2011. ,
LL-37, the neutrophil granule-and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells, J Exp Med, vol.192, pp.1069-74, 2000. ,
Human ?-defensin-3 increases the expression of interleukin-37 through CCR6 in human keratinocytes, J Dermatol Sci, vol.77, pp.46-53, 2015. ,
Leukotriene B4/ antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1, FASEB J, vol.25, pp.1697-705, 2011. ,
Antimicrobial peptide LL-37 promotes bacterial phagocytosis by human macrophages, J Leukoc Biol, vol.95, pp.971-81, 2014. ,
Identification and characterization of a novel antimicrobial peptide from the venom of the ant Tetramorium bicarinatum, Peptides, vol.38, pp.363-70, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00996401
The chemokine system in diverse forms of macrophage activation and polarization, Trends Immunol, vol.25, pp.677-86, 2004. ,
Macrophage activation and polarization, Front Biosci, vol.13, pp.453-61, 2008. ,
PPARgamma promotes mannose receptor gene expression in murine macrophages and contributes to the induction of this receptor by IL-13, Immunity, vol.19, pp.329-368, 2003. ,
PPAR? controls dectin-1 expression required for host antifungal defense against Candida albicans, PLoS Pathog, vol.6, p.1000714, 2010. ,
The C-type lectin receptors dectin-1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum, Immunity, vol.38, pp.1038-1087, 2013. ,
LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPAR? ligand synthesis, Nat Commun, vol.6, p.6801, 2015. ,
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors, J Clin Invest, vol.116, pp.1642-50, 2006. ,
Dectin-1 and dectin-2 in innate immunity against fungi, Int Immunol, vol.23, pp.467-72, 2011. ,
Dectin-1 is required for ?-glucan recognition and control of fungal infection, Nat Immunol, vol.8, pp.31-39, 2007. ,
Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans, J Infect Dis, vol.199, pp.1087-96, 2009. ,
C-type lectin receptors orchestrate antifungal immunity, Future Microbiol, vol.8, pp.839-54, 2013. ,
IL-13 attenuates gastrointestinal candidiasis in normal and immunodeficient RAG-2-/-mice via peroxisome proliferator-activated receptor-activation, J Immunol, vol.180, pp.4939-4986, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-00283071
Emerging roles of PPARS in inflammation and immunity, Nat Rev Immunol, vol.2, pp.748-59, 2002. ,
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation, Cell, vol.83, pp.813-822, 1995. ,
PPAR? ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination, PLoS One, vol.5, p.12828, 2010. ,
Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa, J Med Chem, vol.54, pp.4806-4820, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-01962818
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation, Eur J Immunol, vol.37, pp.1642-52, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00166681
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence, Nature, vol.459, pp.433-439, 2009. ,
Modulation of host defense peptide-mediated human mast cell activation by LPS, Innate Immun, vol.22, pp.21-30, 2016. ,
Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptor, Mucosal Immunol, vol.7, pp.177-87, 2014. ,
Cathelicidin LL-37 induces time-resolved release of LTB4 and TXA2 by human macrophages and triggers eicosanoid generation in vivo, FASEB J, vol.28, pp.3456-67, 2014. ,
The modulatory effect of TLR2 on LL-37-induced human mast cells activation, Biochem Biophys Res Commun, vol.470, pp.368-74, 2016. ,
LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature, J Immunol, vol.185, pp.1442-1451, 2010. ,
Cationic peptides from scorpion venom can stimulate and inhibit polymorphonuclear granulocytes, Toxicon, vol.40, pp.183-189, 2002. ,
Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments, EMBO J, vol.24, pp.1277-86, 2005. ,
C-type lectin receptors in antifungal immunity, Trends Microbiol, vol.16, pp.27-32, 2008. ,
Macrophage-specific PPAR? controls alternative activation and improves insulin resistance, Nature, vol.447, pp.1116-1136, 2007. ,
Interactions of fungal pathogens with phagocytes, Nat Rev Microbiol, vol.14, pp.163-76, 2016. ,
Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophages, J Immunol, vol.146, pp.2783-2792, 1991. ,
Immune regulatory activities of fowlicidin-1, a cathelicidin host defense peptide, Mol Immunol, vol.59, pp.55-63, 2014. ,
Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37, J Immunol, vol.176, pp.2455-64, 2006. ,
The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions, J Leukoc Biol, vol.94, pp.159-70, 2013. ,
Mas-related gene X2 (MrgX2) is a novel G protein-coupled receptor for the antimicrobial peptide LL-37 in human mast cells: resistance to receptor phosphorylation, desensitization, and internalization, J Biol Chem, vol.286, pp.44739-44788, 2011. ,
The caspase-1 inflammasome: a pilot of innate immune responses, Cell Host Microbe, vol.4, pp.198-208, 2008. ,
Braut-Boucher F. p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases, Exp Mol Med, vol.41, p.217, 2009. ,
Myeloid C-type lectin receptors in pathogen recognition and host defense, Immunity, vol.34, pp.651-64, 2011. ,
, Frontiers in Immunology | www.frontiersin.org November, vol.8, p.1650, 2017.
The inflammasomes: guardians of the body, Annu Rev Immunol, vol.27, pp.229-65, 2009. ,
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica, Science, vol.320, pp.674-681, 2008. ,
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?, Nat Rev Immunol, vol.10, pp.210-215, 2010. ,
A role for mitochondria in NLRP3 inflammasome activation, Nature, vol.469, pp.221-226, 2011. ,
Antimicrobial proteins in intestine and inflammatory bowel diseases, Intest Res, vol.12, pp.20-33, 2014. ,
Antimicrobial peptides from scorpion venom induce Ca(2+) signaling in HL-60 cells, Biochem Biophys Res Commun, vol.311, pp.90-97, 2003. ,
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP, Cell, vol.65, pp.1043-51, 1991. ,
The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells, J Biol Chem, vol.266, pp.5268-72, 1991. ,